Page last updated: 2024-10-17

guaiacol and Breast Cancer

guaiacol has been researched along with Breast Cancer in 13 studies

Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)
methylcatechol : Any member of the class of catechols carrying one or more methyl substituents.
guaiacol : A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.

Research Excerpts

ExcerptRelevanceReference
" This study aimed to investigate the effects of zingerone on some immune-related parameters in an animal model of breast cancer."8.02Zingerone improves the immune responses in an animal model of breast cancer. ( Hassan, ZM; Jafarzadeh, A; Kazemi, M; Khorramdelazad, H; Nemati, M; Oladpour, O; Rezayati, MT; Taghipour, F, 2021)
"To examine the potential of ferulic acid and 4-vinylguaiacol for inhibiting epidermal growth factor receptor (EGFR) in human breast cancer cells in vitro."7.88Inhibition of epidermal growth factor receptor by ferulic acid and 4-vinylguaiacol in human breast cancer cells. ( Anuradha, R; Geetharani, Y; Gokulapriya, G; Lakshmi, BS; Sathya, S; Sudhagar, S, 2018)
"This study is the first to investigate the anticancer effect of 6-dehydrogingerdione (DGE), an active constituent of dietary ginger, in human breast cancer MDA-MB-231 and MCF-7 cells."7.766-Dehydrogingerdione, an active constituent of dietary ginger, induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human breast cancer cells. ( Chen, CY; Hou, MF; Hsu, YL; Hung, CH; Jong, YJ; Kuo, PL; Tsai, EM, 2010)
"We collected faecal samples from 14 breast cancer patients and 14 healthy subjects."5.72L-norvaline affects the proliferation of breast cancer cells based on the microbiome and metabolome analysis. ( Hu, Y; Li, X; Luo, N; Wu, Y; Zai, H; Zhang, K; Zhang, X; Zhu, Q, 2022)
"Gigantol is a bibenzyl compound derived from several medicinal orchids."5.48Gigantol inhibits Wnt/β-catenin signaling and exhibits anticancer activity in breast cancer cells. ( Li, S; Li, Y; Liu, S; Liu, ZJ; Lu, D; Song, J; Su, Z; Sun, Q; Wang, M; Wang, Z; Yu, S; Zhang, GQ; Zhang, X; Zhou, L, 2018)
" This study aimed to investigate the effects of zingerone on some immune-related parameters in an animal model of breast cancer."4.02Zingerone improves the immune responses in an animal model of breast cancer. ( Hassan, ZM; Jafarzadeh, A; Kazemi, M; Khorramdelazad, H; Nemati, M; Oladpour, O; Rezayati, MT; Taghipour, F, 2021)
"To examine the potential of ferulic acid and 4-vinylguaiacol for inhibiting epidermal growth factor receptor (EGFR) in human breast cancer cells in vitro."3.88Inhibition of epidermal growth factor receptor by ferulic acid and 4-vinylguaiacol in human breast cancer cells. ( Anuradha, R; Geetharani, Y; Gokulapriya, G; Lakshmi, BS; Sathya, S; Sudhagar, S, 2018)
"This study is the first to investigate the anticancer effect of 6-dehydrogingerdione (DGE), an active constituent of dietary ginger, in human breast cancer MDA-MB-231 and MCF-7 cells."3.766-Dehydrogingerdione, an active constituent of dietary ginger, induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human breast cancer cells. ( Chen, CY; Hou, MF; Hsu, YL; Hung, CH; Jong, YJ; Kuo, PL; Tsai, EM, 2010)
"We collected faecal samples from 14 breast cancer patients and 14 healthy subjects."1.72L-norvaline affects the proliferation of breast cancer cells based on the microbiome and metabolome analysis. ( Hu, Y; Li, X; Luo, N; Wu, Y; Zai, H; Zhang, K; Zhang, X; Zhu, Q, 2022)
"Gigantol could inhibit proliferation of BC cells and enhance DDP-induced apoptosis."1.62Gigantol inhibits proliferation and enhances DDP-induced apoptosis in breast-cancer cells by downregulating the PI3K/Akt/mTOR signaling pathway. ( Du, H; Duan, S; Huang, C; Huang, J; Lin, J; Liu, C; Luo, Y; Tao, S; Wang, H; Wei, G; Xing, S; Zhang, X, 2021)
"Gigantol is a bibenzyl compound derived from several medicinal orchids."1.48Gigantol inhibits Wnt/β-catenin signaling and exhibits anticancer activity in breast cancer cells. ( Li, S; Li, Y; Liu, S; Liu, ZJ; Lu, D; Song, J; Su, Z; Sun, Q; Wang, M; Wang, Z; Yu, S; Zhang, GQ; Zhang, X; Zhou, L, 2018)
"Breast cancer is a complex and multifactorial disease."1.46[10]-Gingerol Reverts Malignant Phenotype of Breast Cancer Cells in 3D Culture. ( Cominetti, MR; Fuzer, AM; Lee, SY; Mott, JD, 2017)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's2 (15.38)18.2507
2000's2 (15.38)29.6817
2010's5 (38.46)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Dich, J1
Zahm, SH1
Hanberg, A1
Adami, HO1
Zhu, Q1
Zai, H1
Zhang, K1
Zhang, X3
Luo, N1
Li, X1
Hu, Y1
Wu, Y1
Kazemi, M1
Jafarzadeh, A1
Nemati, M1
Taghipour, F1
Oladpour, O1
Rezayati, MT1
Khorramdelazad, H1
Hassan, ZM1
Huang, J1
Liu, C1
Duan, S1
Lin, J1
Luo, Y1
Tao, S1
Xing, S1
Du, H1
Wang, H1
Huang, C1
Wei, G1
Sudhagar, S1
Sathya, S1
Anuradha, R1
Gokulapriya, G1
Geetharani, Y1
Lakshmi, BS1
Yu, S1
Wang, Z1
Su, Z1
Song, J1
Zhou, L1
Sun, Q1
Liu, S1
Li, S1
Li, Y1
Wang, M1
Zhang, GQ1
Liu, ZJ1
Lu, D1
Fuzer, AM1
Lee, SY1
Mott, JD1
Cominetti, MR1
Hsu, YL1
Chen, CY1
Hou, MF1
Tsai, EM1
Jong, YJ1
Hung, CH1
Kuo, PL1
Nathwani, SM1
Hughes, L1
Greene, LM1
Carr, M1
O'Boyle, NM1
McDonnell, S1
Meegan, MJ1
Zisterer, DM1
Shukla, Y1
Singh, M1
Segura-Aguilar, J1
Castro, V1
Bergman, A1
Flynn, BL1
Flynn, GP1
Hamel, E1
Jung, MK1
Banerji, AP1
Seshadri, R1

Reviews

2 reviews available for guaiacol and Breast Cancer

ArticleYear
Pesticides and cancer.
    Cancer causes & control : CCC, 1997, Volume: 8, Issue:3

    Topics: Animals; Arsenicals; Breast Neoplasms; Carcinogens; Causality; Chlordan; Creosote; DDT; Ditiocarb; F

1997
Cancer preventive properties of ginger: a brief review.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Catechols; Colonic Neoplasms; Fatty Alcohols; Ga

2007

Other Studies

11 other studies available for guaiacol and Breast Cancer

ArticleYear
L-norvaline affects the proliferation of breast cancer cells based on the microbiome and metabolome analysis.
    Journal of applied microbiology, 2022, Volume: 133, Issue:2

    Topics: Breast Neoplasms; Butyric Acid; Cell Proliferation; Feces; Female; Gastrointestinal Microbiome; Guai

2022
Zingerone improves the immune responses in an animal model of breast cancer.
    Journal of complementary & integrative medicine, 2021, Feb-01, Volume: 18, Issue:2

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Guaiacol; Immunity; Mic

2021
Gigantol inhibits proliferation and enhances DDP-induced apoptosis in breast-cancer cells by downregulating the PI3K/Akt/mTOR signaling pathway.
    Life sciences, 2021, Jun-01, Volume: 274

    Topics: Antineoplastic Agents; Apoptosis; Bibenzyls; Breast Neoplasms; Cell Proliferation; Cisplatin; Drug S

2021
Inhibition of epidermal growth factor receptor by ferulic acid and 4-vinylguaiacol in human breast cancer cells.
    Biotechnology letters, 2018, Volume: 40, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Coumaric Acids; ErbB Receptors; Female; G

2018
Gigantol inhibits Wnt/β-catenin signaling and exhibits anticancer activity in breast cancer cells.
    BMC complementary and alternative medicine, 2018, Feb-14, Volume: 18, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; beta Catenin; Bibenzyls; Breast Neoplasms; Cell Line, Tumor; Cell

2018
[10]-Gingerol Reverts Malignant Phenotype of Breast Cancer Cells in 3D Culture.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:9

    Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Down-Regulation; ErbB Receptors; Fatty Alcoh

2017
6-Dehydrogingerdione, an active constituent of dietary ginger, induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human breast cancer cells.
    Molecular nutrition & food research, 2010, Volume: 54, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Breast Neoplasms; Cell C

2010
Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro.
    Oncology reports, 2013, Volume: 29, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Azetidines; beta-Lactams; Breast Neoplasms; Cell D

2013
Effects of four organohalogen environmental contaminants on cytochrome P450 forms that catalyze 4- and 2-hydroxylation of estradiol in the rat liver.
    Biochemical and molecular medicine, 1997, Volume: 60, Issue:2

    Topics: Animals; Breast Neoplasms; Carcinogens, Environmental; Cytochrome P-450 Enzyme System; Environmental

1997
The synthesis and tubulin binding activity of thiophene-based analogues of combretastatin A-4.
    Bioorganic & medicinal chemistry letters, 2001, Sep-03, Volume: 11, Issue:17

    Topics: Antineoplastic Agents; Breast Neoplasms; Colchicine; Drug Screening Assays, Antitumor; Guaiacol; Hum

2001
Relationship between peroxidase activity and steroid receptors in human mammary tumors.
    Neoplasma, 1985, Volume: 32, Issue:5

    Topics: Breast Neoplasms; Charcoal; Dextrans; Electrophoresis, Agar Gel; Female; Guaiacol; Humans; Peroxidas

1985