guaiacol has been researched along with Alloxan Diabetes in 6 studies
Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)
methylcatechol : Any member of the class of catechols carrying one or more methyl substituents.
guaiacol : A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The treatment with zingerone markedly abrogated ROS levels, inhibited the NF-кB activation and considerably reduced level of other downstream inflammatory molecules (TNF-α, IL-6, IL-1β), furthermore, zingerone treatment improved renal functioning by significantly decreasing the levels of kidney toxicity markers KIM-1, BUN, creatinine, and LDH and suppressed TGF-β." | 5.51 | Zingerone (4-(4-hydroxy-3-methylphenyl)butan-2-one) ameliorates renal function via controlling oxidative burst and inflammation in experimental diabetic nephropathy. ( Ahmad, B; Ahmad, SB; Bhat, SA; Ganaie, MA; Madkhali, H; Majid, S; Rashid, SM; Rasool, S; Rehman, MU; Shakeel, S, 2019) |
| "Zingerone-treated diabetic groups exhibited significant reduction in LPO levels and restoration of GSH contents." | 1.62 | Modulatory effect of zingerone against STZ-nicotinamide induced type-2 diabetes mellitus in rats. ( Alkarbi, ZA; Alshahrani, S; Anwer, T; Firoz Alam, M; Hassan Najmi, A; Khan, G; Siddiqui, R, 2021) |
| "Hyperlipidemia represents a major risk factor for cardiovascular diseases leading to myocardial injury (MI)." | 1.56 | Early myocardial injury biomarkers in diabetic hyperlipidemic rats: Impact of 10-dehydrogingerdione and vitamin D3. ( Aly, SI; Elseweidy, MM; Hammad, SK; Shershir, NI, 2020) |
| "The treatment with zingerone markedly abrogated ROS levels, inhibited the NF-кB activation and considerably reduced level of other downstream inflammatory molecules (TNF-α, IL-6, IL-1β), furthermore, zingerone treatment improved renal functioning by significantly decreasing the levels of kidney toxicity markers KIM-1, BUN, creatinine, and LDH and suppressed TGF-β." | 1.51 | Zingerone (4-(4-hydroxy-3-methylphenyl)butan-2-one) ameliorates renal function via controlling oxidative burst and inflammation in experimental diabetic nephropathy. ( Ahmad, B; Ahmad, SB; Bhat, SA; Ganaie, MA; Madkhali, H; Majid, S; Rashid, SM; Rasool, S; Rehman, MU; Shakeel, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nam, YH | 1 |
| Hong, BN | 1 |
| Rodriguez, I | 1 |
| Park, MS | 1 |
| Jeong, SY | 1 |
| Lee, YG | 1 |
| Shim, JH | 1 |
| Yasmin, T | 1 |
| Kim, NW | 1 |
| Koo, YT | 1 |
| Lee, SH | 1 |
| Paik, DH | 1 |
| Jeong, YJ | 1 |
| Jeon, H | 1 |
| Kang, SC | 1 |
| Baek, NI | 1 |
| Kang, TH | 1 |
| Elseweidy, MM | 1 |
| Aly, SI | 1 |
| Hammad, SK | 1 |
| Shershir, NI | 1 |
| El-Bassossy, HM | 2 |
| Al-Thubiani, WS | 1 |
| Elberry, AA | 2 |
| Mujallid, MI | 1 |
| Ghareib, SA | 2 |
| Azhar, AS | 1 |
| Banjar, ZM | 2 |
| Watson, ML | 2 |
| Rehman, MU | 1 |
| Rashid, SM | 1 |
| Rasool, S | 1 |
| Shakeel, S | 1 |
| Ahmad, B | 1 |
| Ahmad, SB | 1 |
| Madkhali, H | 1 |
| Ganaie, MA | 1 |
| Majid, S | 1 |
| Bhat, SA | 1 |
| Anwer, T | 1 |
| Alkarbi, ZA | 1 |
| Hassan Najmi, A | 1 |
| Alshahrani, S | 1 |
| Siddiqui, R | 1 |
| Khan, G | 1 |
| Firoz Alam, M | 1 |
| Azhar, A | 1 |
| Alahdal, AM | 1 |
6 other studies available for guaiacol and Alloxan Diabetes
| Article | Year |
|---|---|
Steamed Ginger May Enhance Insulin Secretion through K
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fatty Alcohols; Guaiacol; Hypoglycemic Agen | 2020 |
Early myocardial injury biomarkers in diabetic hyperlipidemic rats: Impact of 10-dehydrogingerdione and vitamin D3.
Topics: Animals; Aorta; Biomarkers; Blood Glucose; Cholecalciferol; Diabetes Mellitus, Experimental; Fatty A | 2020 |
Zingerone alleviates the delayed ventricular repolarization and AV conduction in diabetes: Effect on cardiac fibrosis and inflammation.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Electrocardiography; Fibrosis; Guaiacol; He | 2017 |
Zingerone (4-(4-hydroxy-3-methylphenyl)butan-2-one) ameliorates renal function via controlling oxidative burst and inflammation in experimental diabetic nephropathy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Gen | 2019 |
Modulatory effect of zingerone against STZ-nicotinamide induced type-2 diabetes mellitus in rats.
Topics: Animals; Antibiotics, Antineoplastic; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Melli | 2021 |
Protective effect of zingerone on increased vascular contractility in diabetic rat aorta.
Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Guaiacol; Male; P | 2016 |