gsk-7975a has been researched along with Pulmonary-Disease--Chronic-Obstructive* in 1 studies
1 other study(ies) available for gsk-7975a and Pulmonary-Disease--Chronic-Obstructive
| Article | Year |
|---|---|
Bronchial Epithelial Calcium Metabolism Impairment in Smokers and Chronic Obstructive Pulmonary Disease. Decreased ORAI3 Signaling.
The airway epithelium represents a fragile environmental interface potentially disturbed by cigarette smoke (CS), the major risk factor for developing chronic obstructive pulmonary disease (COPD). CS leads to bronchial epithelial damage on ciliated, goblet, and club cells, which could involve calcium (Ca Topics: Adult; Aged; Benzamides; Bronchi; Calcium; Calcium Channels; Calcium Signaling; Cells, Cultured; Cilia; Cytokines; Endoplasmic Reticulum; Epithelial Cells; Female; Gene Expression Regulation; Humans; Interleukin-8; Male; Middle Aged; Mucin 5AC; Mucus; Pulmonary Disease, Chronic Obstructive; Pyrazoles; Respiratory Mucosa; Signal Transduction; Smoke; Smokers; Smoking | 2019 |