gs-7340 has been researched along with Acquired-Immunodeficiency-Syndrome* in 1 studies
1 review(s) available for gs-7340 and Acquired-Immunodeficiency-Syndrome
| Article | Year |
|---|---|
Severe acute hypokalaemia associated with piperacillin/tazobactam in an HIV-infected patient under antiretroviral therapy with tenofovir alafenamide: case report and literature review.
Piperacillin/tazobactam is a commonly prescribed antimicrobial agent. Tenofovir alafenamide (TAF) is increasingly being used in antiretroviral therapy (ART) of HIV. Herein we report a case of a 57-year-old male with AIDS receiving TAF-containing ART in whom severe refractory hypokalaemia developed after coadministration of piperacillin/tazobactam for suspected hospital-acquired infection. Upon withdrawal of piperacillin/tazobactam, serum potassium concentrations returned to normal within 2 days. Hypokalaemia is a rare adverse effect of piperacillin/tazobactam and may be aggravated with the underlying use of TAF. We also reviewed past reported cases of hypokalaemia after piperacillin/tazobactam administration. We want to highlight that a more cautious approach should be considered when combining piperacillin/tazobactam and TAF in clinical practice. Topics: Acquired Immunodeficiency Syndrome; Alanine; Antiviral Agents; Humans; Hypokalemia; Male; Middle Aged; Piperacillin, Tazobactam Drug Combination; Tenofovir | 2020 |