gs-7340 and Acidosis--Lactic

gs-7340 has been researched along with Acidosis--Lactic* in 2 studies

Other Studies

2 other study(ies) available for gs-7340 and Acidosis--Lactic

Article	Year
Management Consideration in Drug-Induced Lactic Acidosis. Clinical journal of the American Society of Nephrology : CJASN, 2020, 10-07, Volume: 15, Issue:10 Topics: Acidosis, Lactic; Acute Kidney Injury; Aged; Alanine; Continuous Renal Replacement Therapy; Diabetes Mellitus, Type 2; Female; Heart Failure; HIV Infections; Humans; Oliguria; Reverse Transcriptase Inhibitors; Sodium Bicarbonate; Tenofovir	2020
Tenofovir alafenamide associated fatal lactic acidosis in an autologous hematopoietic stem cell transplant recipient. Transplant infectious disease : an official journal of the Transplantation Society, 2018, Volume: 20, Issue:5 Fatal lactic acidosis has been reported while on the treatment with Nucleoside/nucleotide analogues (NA) for the treatment of hepatitis B, C and HIV. No cases of such a complication have been reported in hematopoietic stem cell transplant (HSCT) recipients. We present a 65-year male who underwent autologous HSCT for the treatment of multiple myeloma. Prior to transplant he was started on single agent tenofovir alafenamide (TAF) for treatment of resolved hepatitis B infection. He presented few weeks later with severe lactic acidosis. Other causes of lactic acidosis were excluded. The patient died of multi-organ failure despite stopping TAF and aggressive supportive care. The case demonstrates the need for increased awareness of this potential complication of NA treatment in the course of transplantation. Topics: Acidosis, Lactic; Adenine; Aged; Alanine; Antiviral Agents; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Hepatitis B; Hepatitis C; HIV Infections; Humans; Male; Multiple Myeloma; Tenofovir; Transplantation, Autologous	2018

Article

Year

Management Consideration in Drug-Induced Lactic Acidosis.

Clinical journal of the American Society of Nephrology : CJASN, 2020, 10-07, Volume: 15, Issue:10

Topics: Acidosis, Lactic; Acute Kidney Injury; Aged; Alanine; Continuous Renal Replacement Therapy; Diabetes Mellitus, Type 2; Female; Heart Failure; HIV Infections; Humans; Oliguria; Reverse Transcriptase Inhibitors; Sodium Bicarbonate; Tenofovir

2020

Tenofovir alafenamide associated fatal lactic acidosis in an autologous hematopoietic stem cell transplant recipient.

Transplant infectious disease : an official journal of the Transplantation Society, 2018, Volume: 20, Issue:5

Fatal lactic acidosis has been reported while on the treatment with Nucleoside/nucleotide analogues (NA) for the treatment of hepatitis B, C and HIV. No cases of such a complication have been reported in hematopoietic stem cell transplant (HSCT) recipients. We present a 65-year male who underwent autologous HSCT for the treatment of multiple myeloma. Prior to transplant he was started on single agent tenofovir alafenamide (TAF) for treatment of resolved hepatitis B infection. He presented few weeks later with severe lactic acidosis. Other causes of lactic acidosis were excluded. The patient died of multi-organ failure despite stopping TAF and aggressive supportive care. The case demonstrates the need for increased awareness of this potential complication of NA treatment in the course of transplantation.

Topics: Acidosis, Lactic; Adenine; Aged; Alanine; Antiviral Agents; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Hepatitis B; Hepatitis C; HIV Infections; Humans; Male; Multiple Myeloma; Tenofovir; Transplantation, Autologous

2018