griseofulvin and Lupus-Erythematosus--Discoid

Because griseofulvin is one of the safest systemic medications, its side effects are often forgotten. This paper serves as a reminder that griseofulvin can precipitate or exacerbate lupus erythematosus. Two patients are described: one had a photosensitivity reaction to griseofulvin which precipitated discoid LE skin lesions, without any previous evidence of LE. The other, who had known systemic LE, developed a systemic reaction, consisting of fever and malasise.

Topics: Griseofulvin; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Male; Middle Aged; Photosensitivity Disorders

Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Antifungal Agents; Child; Dermatitis, Contact; Facial Dermatoses; Female; Griseofulvin; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Male; Middle Aged; Time Factors; Tinea

Topics: Administration, Oral; Adult; Age Factors; Child; Dermatitis, Contact; Diagnosis, Differential; Diagnostic Errors; Facial Dermatoses; Female; Griseofulvin; Humans; Lupus Erythematosus, Discoid; Male; Tinea; Trichophyton

Topics: Adult; Aged; Dermatomycoses; Female; Griseofulvin; Humans; Lupus Erythematosus, Discoid; Male; Middle Aged

Topics: Adolescent; Copper; Dermatitis; Dermatomycoses; Diagnosis, Differential; Drug Therapy; Erythema; Griseofulvin; Humans; Lupus Erythematosus, Discoid; Psoriasis; Skin Diseases, Genetic; Triamcinolone