griseofulvin and Lichen-Planus--Oral

We report a case of superficial mycosis superimposing on isolated lichen planus (LP) of the lower lip that was successfully treated. A 36-year-old woman had 2 ulcerated, scaling, erythematous plaques on the lower lip for several months with mild painful sensation. Results of histologic study showed typical features of LP, but fungal hyphae were found in the horny layer. The lesion healed with only very mild residual erythema after 6 weeks of treatment. A review of the literature shows only one noted case of tinea of the lip, which was reported in 1968 by a dental practitioner, and only several cases of isolated LP of the lip. The possible mechanism of coexistence of tinea and LP of the lip is reviewed.

Topics: Adult; Anti-Inflammatory Agents; Antifungal Agents; Candidiasis; Diagnosis, Differential; Female; Griseofulvin; Humans; Ketoconazole; Lichen Planus, Oral; Lip; Prednisolone; Treatment Outcome

Lichen planus is a common oral dermatosis and it is one frequently encountered by oral surgeons. Lichen planus can be very difficult to treat, particularly when symptomatic in its erosive and ulcerated forms. This article describes several treatment modalities in the control of oral lichen planus including steroids, griseofulvin, vitamin A, cyclosporine, surgical excision, et al. Other features included consist of proper biopsy site selection, the need for annual re-examination, lichen planus's malignant potential, and when "not to treat."

Topics: Biopsy; Cell Transformation, Neoplastic; Cyclosporine; Griseofulvin; Humans; Lichen Planus, Oral; Steroids; Vitamin A