griseofulvin and Facial-Dermatoses

Tinea barbae is an uncommon superficial dermatophyte infection of the beard and moustache areas. It was more frequently observed in the past, before single-use razors became available. In most cases, the zoophilic ectothrix Trichophyton mentagrophytes and Trichophyton verrucosum are responsible for this type of infection. Its clinical presentation is variable; it can mimic many other skin disorders such as sycosis, iododerma, contact dermatitis, perioral dermatitis, and actinomycosis. We report a case of tinea barbae caused by an uncommon agent Trichophyton rubrum, misdiagnosed as sycosis, and review the approach and management of the disease.

Topics: Aged; Antifungal Agents; Diagnostic Errors; Facial Dermatoses; Facial Injuries; Folliculitis; Griseofulvin; Humans; Male; Tinea; Trichophyton; Wound Infection

Therapy for kerions was evaluated by randomly assigning 30 patients to one of four treatment groups: group A griseofulvin, group B griseofulvin plus erythromycin, group C griseofulvin plus prednisone, and group D griseofulvin, erythromycin, and prednisone. Data indicate that antibiotic and steroid therapy, in addition to griseofulvin, may reduce scaling and pruritus, but does not reduce the time it takes for kerions to flatten.

Topics: Administration, Oral; Child; Double-Blind Method; Drug Combinations; Erythromycin; Facial Dermatoses; Follow-Up Studies; Griseofulvin; Humans; Pilot Projects; Placebos; Prednisone; Staphylococcus aureus; Tinea Capitis; Trichophyton

Majocchi granuloma (MG) is a rare dermal and subcutaneous fungal infection. We report a rare case of MG on the face of a six-year-old child caused by Trichophyton mentagrophytes after long term use of topical corticosteroids and other inadequate topical medications. He was treated with griseofulvin 25 mg/kg/day for 35 days unsuccessfully and successful treatment was obtained with terbinafine.

Topics: Antifungal Agents; Child; Dermatomycoses; Facial Dermatoses; Griseofulvin; Humans; Male; Terbinafine; Tinea; Treatment Failure

Topics: Administration, Oral; Antifungal Agents; Child, Preschool; Facial Dermatoses; Fluconazole; Griseofulvin; Humans; Male; Prognosis; Recurrence; Retreatment; Risk Assessment; Severity of Illness Index; Tinea; Treatment Outcome

To present the common features of periocular tinea to aid physicians in future diagnosis and therapy of this condition, because superficial fungal infections on the face are often misdiagnosed owing to the diverse morphologies that they manifest. This is especially true of dermatophytoses involving the periocular region.. A retrospective review was performed of patients with a diagnosis of periocular tinea who were seen between January 2003 and September 2009 in the pediatric dermatology clinic at St. Louis Children's Hospital.. Ten cases of periocular tinea were identified (6 male patients and 4 female patients). Common features included prolonged misdiagnosis (all 10 cases), a normal ophthalmologic examination (all 10 cases), and inappropriate corticosteroid application (7 cases). Loss of the eyelashes occurred in all 10 patients. No cases had evidence of other tinea infections on examination. Only 2 cases had the central clearing classically associated with tinea corporis. Seven patients had a potassium hydroxide preparation and/or culture positive for fungal elements. Lesions improved with topical and oral antifungal treatment in all cases, and patients were able to regrow their eyelashes.. Periocular tinea should be considered in the differential diagnosis for periocular inflammation, especially in those patients refractory to therapy for more common conditions. Loss of the eyelashes is characteristic of these fungal infections, similar to the hair loss that occurs in kerions associated with tinea capitis.

Topics: Antifungal Agents; Child; Child, Preschool; Dermatitis, Perioral; Diagnosis, Differential; Econazole; Eczema; Eye Infections, Fungal; Eyelashes; Eyelid Diseases; Facial Dermatoses; Female; Griseofulvin; Humans; Impetigo; Male; Ointments; Retrospective Studies; Tinea

The term Tinea Faciei (TF) designates a superficial dermatophyte infection of the glabrous skin of the face, characterized by clinical polymorphism. The aim of the present study is to assess epidemiologic, clinical, mycological, and therapeutic characteristics of TF in a Tunisian dermatology department.. This retrospective study examined the records of cases of TF observed in our dermatology department over the past 5 years (2003-2007).. Fourteen patients with TF were seen during the study period. The sex ratio (5 male/9 female) was 0.56. The average age of these 4 children and 10 adults was 22 years. While the clinical form was typical of TF in 10 cases, 4 patients had a clinical form modified by topical steroids (Tinea incognito). Direct microscopic examination showed hyphal elements in 12 cases, and the mycological culture was positive for 11. Five patients had Trichophyton Violaceum, and 4 T. Mentagrophytes.. TF is frequently misdiagnosed because of its variable appearance. Atypical forms known as tinea incognito are observed after modification of the dermatophyte infections by corticosteroid treatment. Our study included 4 cases of Tinea incognito. T. Mentagrophytes and T. Rubrum are the agents reported most frequently. Unusually, T. Violaceum was found most frequently in our series.

Topics: Adolescent; Adult; Antifungal Agents; Child; Child, Preschool; Facial Dermatoses; Female; Griseofulvin; Humans; Male; Middle Aged; Retrospective Studies; Tinea; Trichophyton; Tunisia; Young Adult

Four cases of tinea faciei that were observed at the Department of Dermatology of Charles Nicolle Hospital in Tunis are reported. All patients were females, ages 54 (patient 1), 38 (patient 2), 30 (patient 3), and 50 (patient 4). The lesions lasted 1 year, 2 months, 4 months, and 1 month, respectively. Tinea faciei was initially suspected in three patients, whereas for the second patient eczema was initially suspected. She was first treated topically with corticosteroids leading to exacerbation. Through mycological examination, Trichophyton rubrum was isolated in three patients, but was negative in patient 2. Three patients recovered completely after one month of griseofulvin associated with topical terbinafine. Patient 3 was topically treated because she was pregnant. Erythematous lesions of the face must be checked for fungi.

Topics: Adult; Antifungal Agents; Facial Dermatoses; Female; Griseofulvin; Humans; Middle Aged; Naphthalenes; Terbinafine; Tinea; Trichophyton; Tunisia

Topics: Antifungal Agents; Facial Dermatoses; Female; Griseofulvin; Humans; Infant, Newborn; Tinea; Tinea Capitis

We describe the case of a 45-year-old man with atopy who developed marked inflammatory lesions on the bearded area of the face caused by Tricophyton rubrum, an anthropophilic fungus not frequently correlated with kerion of the face. After starting therapy with griseofulvin, he developed typical lesions of erythema nodosum on both legs. We discuss how these lesions could be correlated with the kerion of the face.

Topics: Antifungal Agents; Erythema Nodosum; Facial Dermatoses; Griseofulvin; Humans; Male; Middle Aged; Tinea

We report a case of tinea of the face caused by Trichophyton rubrum in which the histologic changes were consistent with granuloma faciale. We recommend that local infection with dermatophytes be considered in all cases of histologic granuloma faciale, especially when the clinical presentation is atypical for this dermatosis.

Topics: Child; Econazole; Environmental Exposure; Facial Dermatoses; Granuloma; Griseofulvin; Humans; Male; Recurrence; Sunlight; Tinea

Topics: Adult; Chin; Epidermophyton; Facial Dermatoses; Griseofulvin; Hair; Humans; Male; Tinea

Report on a 48-year-old man, incidentally occupied as a farmer who was infected by one of his calves. Due to insufficient therapy he produced an expanded tinea barbae.

Topics: Agricultural Workers' Diseases; Animals; Facial Dermatoses; Griseofulvin; Humans; Male; Middle Aged; Tinea; Zoonoses

42 patients suffering from dermatophytic fungus infection involving the bearded area, face and neck (tinea barbae) were seen in the Clinic between 1970 and 1977. The clinical diagnosis was confirmed by microscopic examination (KOH) of skin and hair scrapings in all the patients. The material obtained from 39 patients and inoculated gave a positive culture; in were isolated and following fungi: T rubrum-18, T. mentagrophytes-16, T. megninii-1, T. violaceum-2, M. canis-2. From the clinical point of veiw it was possible to classify the patients in 3 main types: --Superficial type-11 patients. --Kerion-10 patients (T. mentagrophytes-9, M. canis-1). --Nodular type-deep seated nodules, without discharging, very slow evolution - 21 patients (T. mentagrophytes-4, T. rubrum-13, T. megninii-1, T. violaceum-1). It was obtained material for histology in 13 patients: 3 suffering from kerion and 10 with the nodular clinical type. The histology of the Kerion type showed a marked inflammatory reaction consisting largely of neutrophils surrounding the hair follicles. Only in one examination, out of the 3 patients studied with Kerion, showed fungi, on PAS. The 10 patients suffering from the nodular type of infection who were studied histologically showed a more or less uniform picture, which consisted in a more deep seated infiltration specially consisting of lymphocytes and plasmocytes, on the derme but not so perifollicular as in Kerion and, in 2 cases, there was a tendency to form a tuberculoid structure. The PAS was positive in 6 patients. The fungi were always intrafollicular. All the patients were treated with griseofulvin 1 gr. per day. All of them healed after a period of 4-8 weeks of treatment.

Topics: Adolescent; Adult; Aged; Animals; Cattle; Disease Vectors; Dogs; Facial Dermatoses; Folliculitis; Griseofulvin; Humans; Male; Microsporum; Middle Aged; Rabbits; Tinea; Trichophyton

Topics: Erythromycin; Facial Dermatoses; Griseofulvin; Humans; Prednisone; Tinea

The case of a 34-year-old white woman with tinea facialis that persisted for nine months prior to diagnosis is presented. The confluent plaquelike erythematous eruption of the face with eyelid lichenification that flared outdoors was thought to represent polymorphic light eruption and was refractory to antibiotics, corticosteroids (topical and systemic), and antimalarials. A KOH preparation was positive when the dermatosis spilled onto the mandibular region, and restaining of the initial skin biopsy revealed fungal hyphae. Complete resolution was accomplished with griseofulvin and MicTin. Tinea cab be added to the list of infectious agents that have a photosensitivity component. The fungus possibly "photolocalizes" to sun-damaged areas, ie, areas of increased capillary permeability. This case illustrates the importance of including tinea in considering diagnoses of sun-exposed lesions of the face.

Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Diagnosis, Differential; Facial Dermatoses; Female; Glucocorticoids; Griseofulvin; Humans; Microsporum; Photosensitivity Disorders; Tinea

Topics: Adolescent; Adult; Child; Child, Preschool; Dermatomycoses; Facial Dermatoses; Female; Griseofulvin; Humans; Male; Microsporum; Scalp Dermatoses; Siberia

Topics: Adrenal Cortex Hormones; Aged; Facial Dermatoses; Granuloma; Griseofulvin; Humans; Leukemia, Lymphoid; Male; Tinea

Topics: Biopsy; Collagen Diseases; Dermatomyositis; Diagnosis, Differential; Erythema; Facial Dermatoses; Female; Griseofulvin; Humans; Hydroxides; Lupus Erythematosus, Systemic; Middle Aged; Physical Examination; Potassium; Skin; Telangiectasis; Tinea; Tolnaftate; Trichophyton

Topics: Administration, Oral; Adolescent; Adult; Aged; Antifungal Agents; Benzyl Compounds; Child; Child, Preschool; Dermatomycoses; Ethers; Facial Dermatoses; Female; Griseofulvin; Humans; Imidazoles; Infant; Male; Middle Aged; Nitrates; Ointments; Powders; Tinea

Topics: Antifungal Agents; Facial Dermatoses; Griseofulvin; Humans; Male; Tinea

Topics: Cheek; Eye Diseases; Eyelid Diseases; Facial Dermatoses; Female; Griseofulvin; Humans; Middle Aged; Tinea; Tolnaftate; Trichophyton

Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Antifungal Agents; Child; Dermatitis, Contact; Facial Dermatoses; Female; Griseofulvin; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Male; Middle Aged; Time Factors; Tinea

Topics: Administration, Oral; Adult; Age Factors; Child; Dermatitis, Contact; Diagnosis, Differential; Diagnostic Errors; Facial Dermatoses; Female; Griseofulvin; Humans; Lupus Erythematosus, Discoid; Male; Tinea; Trichophyton

Topics: Aged; Antifungal Agents; Facial Dermatoses; Griseofulvin; Hair; Humans; Male; Ointments; Tinea

Topics: Adult; Buttocks; Dermatomycoses; Europe, Eastern; Extremities; Facial Dermatoses; Folliculitis; France; Griseofulvin; Humans; Male; Portugal; Skin; Spain; Trichophyton

Topics: Animals; Anti-Bacterial Agents; Culture Techniques; Environmental Exposure; Facial Dermatoses; Griseofulvin; Humans; Leg Dermatoses; Male; Mice; Middle Aged; Potassium Iodide; Sporothrix; Sporotrichosis

Topics: Child; Facial Dermatoses; Female; Germany, West; Griseofulvin; Humans; Tinea; Trichophyton