griseofulvin and Dermatomyositis

Curvularia spp. are globally distributed saprophytic fungi, classified in the literature as dematiaceous, or darkly pigmented fungi. These fungi have been increasingly recognized as causing cutaneous, ocular, respiratory, and central nervous system infections in humans, but have been infrequently documented as pathogens in the veterinary literature. A 5-yr-old male Chinese goral (

Topics: Animals; Animals, Zoo; Antifungal Agents; Clotrimazole; Dermatomyositis; Griseofulvin; Male; Rhinitis; Ruminants; Sinusitis

Skin eruptions with features of subacute cutaneous lupus erythematosus occurred in a patient with dermatomyositis who was taking griseofulvin. The patient had antibodies against SSA/Ro and SSB/La antigens. Skin rashes disappeared after discontinuation of griseofulvin and recurred on challenge with the drug. These findings support previous studies that the photoactive drug may be synergistic with anti-SSA/Ro antibody to produce lesions of subacute cutaneous lupus erythematosus.

Topics: Adult; Biopsy; Dermatomyositis; Drug Eruptions; Female; Griseofulvin; Humans; Keratins; Lupus Erythematosus, Cutaneous; Skin

Topics: Biopsy; Collagen Diseases; Dermatomyositis; Diagnosis, Differential; Erythema; Facial Dermatoses; Female; Griseofulvin; Humans; Hydroxides; Lupus Erythematosus, Systemic; Middle Aged; Physical Examination; Potassium; Skin; Telangiectasis; Tinea; Tolnaftate; Trichophyton

Topics: Dermatomycoses; Dermatomyositis; Griseofulvin; Humans; Skin

Topics: Dermatomycoses; Dermatomyositis; Griseofulvin; Humans; Skin