griseofulvin and Brain-Diseases

A case of massive cerebral aspergillosis complicating a frontal encephalomeningocele is reported. The etiology and pathogenesis are discussed and the diagnosis, symptoms, and treatment possibilities reviewed.

Topics: Aspergillosis; Aspergillus fumigatus; Brain Diseases; Child, Preschool; Encephalocele; Griseofulvin; Humans; Male; Meningocele; Postoperative Complications

An ominous prognosis is associated with combined pulmonary and rhinocerebral mucormycosis (phycomycosis). We report the case of a diabetic patient with ketoacidosis who had extensive pulmonary and rhinocerebral mucormycosis that responded satisfactorily to amphotericin B and griseofulvin therapy. The affected lung is completely atelectatic and has remained so for 12 months without evidence of necrosis or abscess formation.

Topics: Adult; Amphotericin B; Brain Diseases; Diabetic Ketoacidosis; Female; Griseofulvin; Humans; Lung Diseases, Fungal; Mucormycosis; Nose Diseases; Prognosis