grifolin and Alzheimer-Disease

grifolin has been researched along with Alzheimer-Disease* in 2 studies

Other Studies

2 other study(ies) available for grifolin and Alzheimer-Disease

ArticleYear
Inhibition of BACE1 and Amyloid-β Aggregation by Meroterpenoids from the Mushroom
    Journal of natural products, 2021, 06-25, Volume: 84, Issue:6

    To develop drugs to treat Alzheimer's disease (AD) on the basis of the amyloid cascade hypothesis, the amyloid-β (Aβ) aggregation inhibitory activities of 110 extracts from mushrooms were evaluated by thioflavin T (Th-T) assays. The MeOH extract of

    Topics: Agaricales; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Basidiomycota; Humans; Japan; Molecular Structure; Terpenes

2021
Isolation of three new meroterpenoids and seven known compounds from Albatrellus yasudae and their Aβ-aggregation inhibitory activity.
    Bioorganic & medicinal chemistry letters, 2020, 01-15, Volume: 30, Issue:2

    Alzheimer's disease is a serious neurologic disorder that cannot be cured completely. In this study, we targeted compounds that inhibit amyloid-beta (Aβ) aggregation, based on the amyloid cascade hypothesis. Ten compounds (1-10) were isolated from CHCl

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Basidiomycota; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Conformation; Resorcinols; Terpenes

2020