gramicidin-a and Hyperthyroidism

gramicidin-a has been researched along with Hyperthyroidism* in 1 studies

Other Studies

1 other study(ies) available for gramicidin-a and Hyperthyroidism

ArticleYear
The contribution of ATP turnover by the Na+/K+-ATPase to the rate of respiration of hepatocytes. Effects of thyroid status and fatty acids.
    Biochimica et biophysica acta, 1989, Sep-28, Volume: 976, Issue:2-3

    In less than 1 min ouabain maximally inhibits oxygen consumption due to gramicidin-induced ATP turnover by the Na+/K+-ATPase in hepatocytes. Ouabain rapidly inhibits respiration on palmitate or glucose by only 6-10% indicating that the Na+/K+-ATPase plays a minor role in cell ATP turnover. 29% of the extra oxygen consumption of hepatocytes isolated from hyperthyroid rats was inhibited by ouabain showing that the Na+/K+-ATPase is responsible for some but not the majority of the stimulation of respiration induced by thyroid hormone.

    Topics: Adenosine Triphosphate; Animals; Caprylates; Cells, Cultured; Fasting; Female; Gramicidin; Hyperthyroidism; Kinetics; Liver; Ouabain; Oxygen Consumption; Palmitic Acid; Palmitic Acids; Rats; Rats, Inbred Strains; Reference Values; Rubidium; Sodium-Potassium-Exchanging ATPase; Thyroid Gland

1989