gracillin has been researched along with Melanoma in 2 studies
*Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, XL; Li, JK; Wang, Y; Yung, KK; Zhang, Z; Zhu, PL | 1 |
| Hu, K; Yao, X | 1 |
2 other study(ies) available for gracillin and Melanoma
| Article | Year |
|---|---|
Gracillin exerts anti-melanoma effects in vitro and in vivo: role of DNA damage, apoptosis and autophagy.
Topics: Animals; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; DNA Damage; Melanoma; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases | 2023 |
The cytotoxicity of methyl protoneogracillin (NSC-698793) and gracillin (NSC-698787), two steroidal saponins from the rhizomes of Dioscorea collettii var. hypoglauca, against human cancer cells in vitro.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Central Nervous System Neoplasms; Colonic Neoplasms; Dioscorea; Dose-Response Relationship, Drug; Female; Humans; Kidney Neoplasms; Lethal Dose 50; Leukemia; Male; Melanoma; Mice; Phytotherapy; Plant Extracts; Plant Roots; Prostatic Neoplasms; Saponins; Spirostans; Steroids; Tumor Cells, Cultured | 2003 |