Page last updated: 2024-10-28

gr 89696 and Pain

gr 89696 has been researched along with Pain in 2 studies

GR 89696: a potent & selective kappa opioid receptor agonist; RN given refers to (E)-2-butenedioate(1:1); RN for parent cpd not available 11/92; GR 103545 is the (R)-isomer

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Although bone cancer-related pain is one of the most disruptive symptoms in patients with advanced cancer, patients are often refractory to pharmacological treatments; thus, more effective treatments for bone cancer pain are needed."1.37The intrathecally administered kappa-2 opioid agonist GR89696 and interleukin-10 attenuate bone cancer-induced pain through synergistic interaction. ( Cui, JH; Jeong, CW; Kim, WM; Kim, YO; Lee, SH; Yoon, MH, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, WM1
Jeong, CW1
Lee, SH1
Kim, YO1
Cui, JH1
Yoon, MH1
Eliav, E1
Herzberg, U1
Caudle, RM1

Other Studies

2 other studies available for gr 89696 and Pain

ArticleYear
The intrathecally administered kappa-2 opioid agonist GR89696 and interleukin-10 attenuate bone cancer-induced pain through synergistic interaction.
    Anesthesia and analgesia, 2011, Volume: 113, Issue:4

    Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Behavior, Animal; Bone Neoplasms; Breast Neop

2011
The kappa opioid agonist GR89,696 blocks hyperalgesia and allodynia in rat models of peripheral neuritis and neuropathy.
    Pain, 1999, Volume: 79, Issue:2-3

    Topics: Analgesics, Non-Narcotic; Animals; Cold Temperature; Hot Temperature; Hyperalgesia; Injections, Spin

1999