gr 89696 has been researched along with Disease Models, Animal in 5 studies
GR 89696: a potent & selective kappa opioid receptor agonist; RN given refers to (E)-2-butenedioate(1:1); RN for parent cpd not available 11/92; GR 103545 is the (R)-isomer
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "First, a dose-response curve for analgesic efficacy was generated for each opioid agonist." | 1.43 | Evaluation of the effects of specific opioid receptor agonists in a rodent model of spinal cord injury. ( Aceves, M; Hook, MA; Mathai, BB, 2016) |
| "Although bone cancer-related pain is one of the most disruptive symptoms in patients with advanced cancer, patients are often refractory to pharmacological treatments; thus, more effective treatments for bone cancer pain are needed." | 1.37 | The intrathecally administered kappa-2 opioid agonist GR89696 and interleukin-10 attenuate bone cancer-induced pain through synergistic interaction. ( Cui, JH; Jeong, CW; Kim, WM; Kim, YO; Lee, SH; Yoon, MH, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Popov, SV | 1 |
| Mukhomedzyanov, AV | 1 |
| Tsibulnikov, SY | 1 |
| Khaliuli, I | 1 |
| Oeltgen, PR | 1 |
| Prasad, NR | 1 |
| Maslov, LN | 1 |
| Aceves, M | 1 |
| Mathai, BB | 1 |
| Hook, MA | 1 |
| Kim, WM | 1 |
| Jeong, CW | 1 |
| Lee, SH | 1 |
| Kim, YO | 1 |
| Cui, JH | 1 |
| Yoon, MH | 1 |
5 other studies available for gr 89696 and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Activation of Peripheral Opioid Kappa1 Receptor Prevents Cardiac Reperfusion Injury.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Administra | 2021 |
Evaluation of the effects of specific opioid receptor agonists in a rodent model of spinal cord injury.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Body Weight; Disease Models, Animal; Dose-Respons | 2016 |
The intrathecally administered kappa-2 opioid agonist GR89696 and interleukin-10 attenuate bone cancer-induced pain through synergistic interaction.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Behavior, Animal; Bone Neoplasms; Breast Neop | 2011 |