gossypol has been researched along with Zika Virus Infection in 3 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Zika Virus Infection: A viral disease transmitted by the bite of AEDES mosquitoes infected with ZIKA VIRUS. Its mild DENGUE-like symptoms include fever, rash, headaches and ARTHRALGIA. The viral infection during pregnancy, in rare cases, is associated with congenital brain and ocular abnormalities, called Congenital Zika Syndrome, including MICROCEPHALY and may also lead to GUILLAIN-BARRE SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We previously identified gossypol as an effective inhibitor against ZIKV and DENV infections, but this compound is toxic and not suitable for in vivo treatment." | 5.72 | A gossypol derivative effectively protects against Zika and dengue virus infection without toxicity. ( Chen, S; Debnath, AK; Du, L; Gao, Y; Jiang, S; Tai, W; Wang, X, 2022) |
| " We previously identified gossypol as an effective inhibitor against ZIKV and DENV infections, but this compound is toxic and not suitable for in vivo treatment." | 1.72 | A gossypol derivative effectively protects against Zika and dengue virus infection without toxicity. ( Chen, S; Debnath, AK; Du, L; Gao, Y; Jiang, S; Tai, W; Wang, X, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Gao, Y | 2 |
| Tai, W | 2 |
| Wang, X | 1 |
| Jiang, S | 2 |
| Debnath, AK | 2 |
| Du, L | 2 |
| Chen, S | 2 |
| Wang, N | 1 |
| Li, X | 1 |
3 other studies available for gossypol and Zika Virus Infection
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
A gossypol derivative effectively protects against Zika and dengue virus infection without toxicity.
Topics: Animals; Cross Reactions; Dengue; Dengue Virus; Female; Gossypol; Male; Mice; Pregnancy; Zika Virus; | 2022 |
Identification of Novel Natural Products as Effective and Broad-Spectrum Anti-Zika Virus Inhibitors.
Topics: Alkaloids; Animals; Antiviral Agents; Biological Products; Cell Survival; Chlorocebus aethiops; Curc | 2019 |