gossypol has been researched along with Waldenstrom Macroglobulinemia in 1 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Waldenstrom Macroglobulinemia: A lymphoproliferative disorder characterized by pleomorphic B-LYMPHOCYTES including PLASMA CELLS, with increased levels of monoclonal serum IMMUNOGLOBULIN M. There is lymphoplasmacytic cells infiltration into bone marrow and often other tissues, also known as lymphoplasmacytic lymphoma. Clinical features include ANEMIA; HEMORRHAGES; and hyperviscosity.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paulus, A | 1 |
| Chitta, K | 1 |
| Akhtar, S | 1 |
| Personett, D | 1 |
| Miller, KC | 1 |
| Thompson, KJ | 1 |
| Carr, J | 1 |
| Kumar, S | 1 |
| Roy, V | 1 |
| Ansell, SM | 1 |
| Mikhael, JR | 1 |
| Dispenzieri, A | 1 |
| Reeder, CB | 1 |
| Rivera, CE | 1 |
| Foran, J | 1 |
| Chanan-Khan, A | 1 |
1 other study available for gossypol and Waldenstrom Macroglobulinemia
| Article | Year |
|---|---|
AT-101 downregulates BCL2 and MCL1 and potentiates the cytotoxic effects of lenalidomide and dexamethasone in preclinical models of multiple myeloma and Waldenström macroglobulinaemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tum | 2014 |