gossypol has been researched along with Uterine Neoplasms in 13 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Uterine Neoplasms: Tumors or cancer of the UTERUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "to investigate the effect of gossypol on the growth of cultured human uterine leiomyoma and myometrial cells, the level of Bcl-2 and the activity of Src and estrogen receptor (ERα)." | 7.76 | Involvement of Bcl-2, Src, and ERα in gossypol-mediated growth inhibition and apoptosis in human uterine leiomyoma and myometrial cells. ( CAO, L; CAO, Y; XIE, SW; ZHANG, JF; ZHANG, TT; ZHOU, JY; ZHU, Y, 2010) |
| "Effects of the gossypol on endometriosis in 12 cases of control were observed." | 7.67 | [Clinical effects and experimental study on gossypol in endometriosis]. ( Wang, M; Xu, LF; Zhao, CL, 1989) |
| "to investigate the effect of gossypol on the growth of cultured human uterine leiomyoma and myometrial cells, the level of Bcl-2 and the activity of Src and estrogen receptor (ERα)." | 3.76 | Involvement of Bcl-2, Src, and ERα in gossypol-mediated growth inhibition and apoptosis in human uterine leiomyoma and myometrial cells. ( CAO, L; CAO, Y; XIE, SW; ZHANG, JF; ZHANG, TT; ZHOU, JY; ZHU, Y, 2010) |
| "Gossypol treatment of endometriosis and uterine myomas in 15 cases was started with a daily dose of 20 mg of gossypol-acetic acid twice a day for 20 days as a loading dose, followed by 40 mg (20 mg twice weekly)." | 3.67 | Electron microscopic observations of the effects of gossypol on the human endometrium. ( Cheng, J; Dang, MY; Han, ML; Sun, YT; Tian, L; Zu, PD, 1984) |
| "Effects of the gossypol on endometriosis in 12 cases of control were observed." | 3.67 | [Clinical effects and experimental study on gossypol in endometriosis]. ( Wang, M; Xu, LF; Zhao, CL, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (92.31) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ZHU, Y | 1 |
| XIE, SW | 1 |
| ZHANG, JF | 1 |
| ZHANG, TT | 1 |
| ZHOU, JY | 1 |
| CAO, Y | 1 |
| CAO, L | 1 |
| Han, ML | 6 |
| Wang, YF | 6 |
| Ma, XH | 2 |
| Han, HL | 1 |
| Zu, PD | 1 |
| Sun, YT | 2 |
| Cheng, J | 1 |
| Tian, L | 1 |
| Dang, MY | 1 |
| Cheng, KF | 1 |
| Wu, WY | 1 |
| Tang, MY | 3 |
| Chu, PT | 1 |
| Xu, LF | 1 |
| Wang, M | 1 |
| Zhao, CL | 1 |
| Zhu, YN | 1 |
| Ge, QS | 2 |
| Zhou, LF | 1 |
| Zhu, PD | 1 |
| Ye, XQ | 1 |
| Zhao, Y | 1 |
| Zhang, JC | 1 |
| Ye, LZ | 1 |
| Ma, SW | 1 |
| Luo, HY | 1 |
13 other studies available for gossypol and Uterine Neoplasms
| Article | Year |
|---|---|
Involvement of Bcl-2, Src, and ERα in gossypol-mediated growth inhibition and apoptosis in human uterine leiomyoma and myometrial cells.
Topics: Adult; Apoptosis; Caspase 3; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Es | 2010 |
[Clinical observation of the gossypol treatment of endometriosis and uterine myoma and the location of the pharmacological action].
Topics: Adult; Endometriosis; Endometrium; Female; Gonadotropins, Pituitary; Gossypol; Humans; Leiomyoma; Mi | 1982 |
[A comparative study on rapid and slow loading of gossypol in the treatment of gynecological diseases].
Topics: Adult; Endometriosis; Female; Gossypol; Humans; Leiomyoma; Middle Aged; Ovary; Uterine Neoplasms | 1984 |
[Gossypol treatment for menopausal functional bleeding, myoma of uterus and endometriosis--preliminary report (author's transl)].
Topics: Adult; Endometriosis; Female; Gossypol; Humans; Leiomyoma; Menopause; Middle Aged; Uterine Hemorrhag | 1980 |
Electron microscopic observations of the effects of gossypol on the human endometrium.
Topics: Endocrine Glands; Endometriosis; Endometrium; Female; Gossypol; Humans; Leiomyoma; Menstruation; Tim | 1984 |
Endometrial changes after administration of gossypol for menorrhagia.
Topics: Adult; Atrophy; Endometriosis; Endometrium; Female; Gossypol; Humans; Leiomyoma; Menorrhagia; Middle | 1980 |
[Clinical effects and experimental study on gossypol in endometriosis].
Topics: Adult; Antineoplastic Agents, Phytogenic; Drugs, Chinese Herbal; Endometriosis; Female; Gossypol; Hu | 1989 |
[Ultrastructural changes in smooth muscle cells in leiomyoma and the myometrium of the human uterus after gossypol treatment].
Topics: Adult; Female; Gossypol; Humans; Leiomyoma; Middle Aged; Mitochondria, Muscle; Muscle, Smooth; Myome | 1987 |
[Observation on blood biochemical indices after gossypol treatment in gynecological cases].
Topics: Adult; Cholesterol; Endometriosis; Female; Gossypol; Humans; Leiomyoma; Lipoproteins, HDL; Middle Ag | 1988 |
Gossypol in the treatment of endometriosis and uterine myoma.
Topics: Adult; Endometriosis; Female; Follicle Stimulating Hormone; Follow-Up Studies; Gossypol; Humans; Lei | 1987 |
[Late effect of gossypol treatment in gynecological diseases--a clinical study of 72 cases].
Topics: Adult; Endometriosis; Female; Follow-Up Studies; Gossypol; Humans; Leiomyoma; Medicine, Chinese Trad | 1985 |
[Clinical and experimental study of gossypol in the treatment of dysfunctional menorrhagia, endometriosis and fibromyoma of the uterus].
Topics: Adult; Aged; Animals; Endometriosis; Female; Gossypol; Humans; Leiomyoma; Menorrhagia; Middle Aged; | 1988 |
Studies on frequencies of sister chromatid exchange in peripheral blood lymphocytes before and after gossypol treatment.
Topics: Adult; Endometriosis; Female; Gossypol; Humans; Leiomyoma; Lymphocytes; Middle Aged; Sister Chromati | 1986 |