gossypol has been researched along with Trypanosomiasis, African in 3 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gossypol treatment and trypanosomal infection, either alone or in concert, caused an anaemia that was both macrocytic and hypochromic." | 1.29 | The effects of protein malnutrition and experimental infection with Trypanosoma brucei on gossypol treatment in the rat: haematological and serum biochemical changes. ( Aire, TA; Akingbemi, BT; Ogwuegbu, SO; Oke, BO; Onwuka, SK, 1995) |
| "Gossypol treatment or trypanosome infection, either alone or together, invariably caused significant reductions in the serum activity of creatine phosphokinase and amylase and in the serum concentration of cortisol." | 1.29 | Gossypol toxicosis in the rat associated with protein malnutrition and experimental infection with Trypanosoma brucei. ( Aire, TA; Akingbemi, BT; Ogwuegbu, SO; Oke, BO; Onwuka, SK, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akingbemi, BT | 3 |
| Ogwuegbu, SO | 2 |
| Onwuka, SK | 2 |
| Oke, BO | 3 |
| Aire, TA | 3 |
3 other studies available for gossypol and Trypanosomiasis, African
| Article | Year |
|---|---|
The effects of protein malnutrition and experimental infection with Trypanosoma brucei on gossypol treatment in the rat: haematological and serum biochemical changes.
Topics: Animals; Blood Cell Count; Blood Chemical Analysis; Gossypol; Male; Nutritional Status; Protein Defi | 1995 |
Infection with Trypanosoma brucei potentiates the antifertility effect of gossypol, especially in the protein-malnourished male rat.
Topics: Animals; Body Weight; Genitalia, Male; Gossypol; Infertility, Male; Male; Microscopy, Electron; Orga | 1996 |
Gossypol toxicosis in the rat associated with protein malnutrition and experimental infection with Trypanosoma brucei.
Topics: Adrenal Glands; Amylases; Animals; Contraindications; Creatine Kinase; Gossypol; Heart; Hydrocortiso | 1996 |