gossypol has been researched along with Pregnancy in 53 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intramuscular injections of gossypol acetic acid (25 mg in 10% EtOH/kg/day beginning on day 2 of diestrus) disrupted early pregnancy in rats as determined by light and electron microscopy." | 7.67 | Histopathologic changes of uterus following gossypol treatment during early pregnancy in rats. ( Lin, YC; Rikihisa, Y; Walton, A, 1985) |
| " We previously identified gossypol as an effective inhibitor against ZIKV and DENV infections, but this compound is toxic and not suitable for in vivo treatment." | 5.72 | A gossypol derivative effectively protects against Zika and dengue virus infection without toxicity. ( Chen, S; Debnath, AK; Du, L; Gao, Y; Jiang, S; Tai, W; Wang, X, 2022) |
| " However, when gosyypol was given in combination with misoprostol 400, 800 or 1600 micrograms." | 5.30 | [Effect of gossypol in combination with misoprostol on termination of early pregnancy in rats and mice]. ( Cao, L; Chen, Y; Gu, ZP, 1997) |
| " However, (+) gossypol at the dosage of 40 mg." | 5.29 | [Effect of (+), (-) and (+/-) gossypol on early pregnancy in rats]. ( Guan, MZ; Wang, NG, 1996) |
| "To ascertain whether the side effects of gossypol, hypokalemia and irreversibility, could be avoided on dose reduction." | 5.09 | Low dose gossypol for male contraception. ( Cao, L; Chen, ZX; Gu, ZP; Mao, BY; Segal, SJ; Tan, YZ; Wang, YX; You, GD; Zhang, RA, 2000) |
| " Progesterone formed from pregnenolone by 3β-hydroxysteroid dehydrogenase 1 (HSD3B1) and estradiol from androgen by aromatase (CYP19A1) are critical for the maintenance of pregnancy or associated with some cancers." | 3.83 | Gossypol enantiomers potently inhibit human placental 3β-hydroxysteroid dehydrogenase 1 and aromatase activities. ( Dong, Y; Ge, RS; Guan, H; Huang, P; Li, L; Li, X; Lian, Q; Mao, B; Su, Y, 2016) |
| "A 431-d experiment was conducted to determine the effects of whole cottonseed containing gossypol (7400 mg/kg) on growth and development from weaning until pregnancy in Holstein heifers." | 3.69 | Effect of whole cottonseed on serum constituents, fragility of erythrocyte cells, and reproduction of growing Holstein heifers. ( Colin-Negrete, J; Kiesling, HE; Ross, TT; Smith, JF, 1996) |
| " The control group (n = 5) were injected with vehicle intramuscularly on the 17th, 18th and 19th day of pregnancy, and the gossypol treated group (n = 4) were injected with gossypol acetic acid (GAA) (25 mg/kg of body weight) intramuscularly on the 17th, 18th and 19th day and were decapitated on the 20th day of pregnancy." | 3.68 | Gossypol effects on monoamine oxidase (MAO) activity in several organs of term rats. ( Chin Lin, Y; Furuhashi, N; Gu, Y; Kono, H; Takayama, K; Yajima, A; Yamaguchi, M; Zuspan, FP, 1991) |
| "The effects of gossypol acetic on pregnancy, embryofoetal development and on some selected parameters of immunological response in mice were studied." | 3.67 | The embryotoxic and immunodepressive effects of gossypol. ( Sein, GM, 1986) |
| "Gossypol is a yellowish phenolic compound ocurring naturally in certain species of cotton plants of the family Malvaciae, mostly in the seeds and root bark." | 2.37 | Gossypol: a potential antifertility agent for males. ( Qian, SZ; Wang, ZG, 1984) |
| " We previously identified gossypol as an effective inhibitor against ZIKV and DENV infections, but this compound is toxic and not suitable for in vivo treatment." | 1.72 | A gossypol derivative effectively protects against Zika and dengue virus infection without toxicity. ( Chen, S; Debnath, AK; Du, L; Gao, Y; Jiang, S; Tai, W; Wang, X, 2022) |
| "Gossypol is a polyphenolic compound, commonly found in cotton seeds, that impairs male reproduction." | 1.56 | Gestational and lactational exposure to gossypol alters the testis transcriptome. ( Amorín, R; Corrêa, PS; Ieda, EH; Jimenez, CR; Liu, L; Louvandini, H; McManus, CM; Peñagaricano, F; Tsai, SM, 2020) |
| "Gossypol is a chemical present in the seeds of cotton plants (Gossypium sp." | 1.42 | Mechanisms involved in reproductive damage caused by gossypol in rats and protective effects of vitamin E. ( Bizerra, PF; Guelfi, M; Medeiros, HC; Mingatto, FE; Santana, AT; Tavares, MA, 2015) |
| "The gossypol content was significantly reduced by irradiation in a dose-dependent manner." | 1.32 | Irradiation effects on embryotoxicity and oxidative properties of gossypol dissolved in methanol. ( Byun, MW; Jo, C; Kim, JH; Kwon, JS; Lee, MS; Song, HP; Yook, HS, 2003) |
| "Gossypol in the diet was absorbed by the female trout and transferred to the eggs (0, 2." | 1.31 | Reproductive efficiency and maternal-offspring transfer of gossypol in rainbow trout (Oncorhynchus mykiss) fed diets containing cottonseed meal. ( Blom, JH; Dabrowski, K; Lee, KJ; Ottobre, J; Rinchard, J, 2001) |
| "Gossypol toxicity was evident in cows fed cottonseed meal because erythrocyte fragility was greater than for control cows." | 1.30 | Deleterious actions of gossypol on bovine spermatozoa, oocytes, and embryos. ( Boning, AJ; Brocas, C; Calhoun, MC; Chenoweth, PJ; Hansen, PJ; McDowell, LR; Paula-Lopes, FF; Rivera, RM; Staples, CR; Wilkinson, NS, 1997) |
| " However, when gosyypol was given in combination with misoprostol 400, 800 or 1600 micrograms." | 1.30 | [Effect of gossypol in combination with misoprostol on termination of early pregnancy in rats and mice]. ( Cao, L; Chen, Y; Gu, ZP, 1997) |
| "Gossypol is a potent antifertility agent contained in seeds and other parts of cotton plants." | 1.28 | Characteristics of covalent gossypol binding to microsomal proteins. ( Brueggemeier, RW; Darby, MV; Li, PK; Lin, YC; Moh, PP, 1992) |
| " Treatment of mice with gossypol produced significant adverse effects on the dam and offspring including decreased pregnancy weight gain of the dam and growth retardation of the offspring." | 1.28 | Evidence for embryotoxicity of gossypol in mice and chicks with no evidence of mutagenic activity in the Ames test. ( Booth, GM; Li, YF; Seegmiller, RE, 1989) |
| "Gossypol, a drug which has been shown to be an inhibitor of kinase C activity in mouse mammary tissues, is shown to abolish several of the actions of prolactin in cultured mouse mammary gland explants." | 1.27 | Effect of kinase C inhibitor, gossypol, on the actions of prolactin in cultured mouse mammary tissues. ( Etindi, RN; Rillema, JA, 1987) |
| "Gossypol treatment of males had no effect on the outcome of pregnancy." | 1.27 | A developmental toxicity evaluation of gossypol. ( Beaudoin, AR, 1988) |
| " Overall, based on the limited dosing schedule employed, the minus isomer appears about twice as potent as the racemic mixture." | 1.27 | (-)-Gossypol: an active male antifertility agent. ( Bialy, G; Blye, RP; Lindberg, MC; Matlin, SA; Naqvi, RH; Zhou, R, 1985) |
| "Gossypol treatment of males had no effect on the outcome of pregnancy." | 1.27 | The embryotoxicity of gossypol. ( Beaudoin, AR, 1985) |
| "Gossypol was identified and quantitated in plasma and liver but was not detected in erythrocytes or milk from cows fed cottonseed meal." | 1.26 | Physiological responses of lactating cows to gossypol from cottonseed meal rations. ( Guthrie, LD; Hawkins, GE; Lindsey, TO, 1980) |
| "Gossypol did not inhibit ovulation in the rat at dosages up to 80 mg/kg/day but did cause 90% inhibition of pregnancy in mice treated with 80 mg/kg/day during the first two weeks of pregnancy." | 1.26 | Antifertility and endocrine activities of gossypol in rodents. ( Hahn, DW; Homm, R; Johnson, AN; Probst, A; Rusticus, C, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (49.06) | 18.7374 |
| 1990's | 12 (22.64) | 18.2507 |
| 2000's | 8 (15.09) | 29.6817 |
| 2010's | 3 (5.66) | 24.3611 |
| 2020's | 4 (7.55) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, Y | 1 |
| Tai, W | 1 |
| Wang, X | 1 |
| Jiang, S | 1 |
| Debnath, AK | 1 |
| Du, L | 1 |
| Chen, S | 1 |
| Louvandini, H | 2 |
| Corrêa, PS | 2 |
| Amorín, R | 1 |
| Liu, L | 1 |
| Ieda, EH | 1 |
| Jimenez, CR | 2 |
| Tsai, SM | 1 |
| McManus, CM | 1 |
| Peñagaricano, F | 1 |
| Zhu, X | 1 |
| Wu, Y | 1 |
| Pan, J | 1 |
| Li, C | 1 |
| Huang, J | 1 |
| Cui, E | 1 |
| Chen, Z | 1 |
| Zhou, W | 1 |
| Chai, X | 1 |
| Zhao, S | 1 |
| Moretti, DB | 1 |
| da Silva, TP | 1 |
| da Costa, RLD | 1 |
| Siu, TM | 1 |
| Santana, AT | 1 |
| Guelfi, M | 1 |
| Medeiros, HC | 1 |
| Tavares, MA | 1 |
| Bizerra, PF | 1 |
| Mingatto, FE | 1 |
| Dong, Y | 1 |
| Mao, B | 1 |
| Li, L | 1 |
| Guan, H | 1 |
| Su, Y | 1 |
| Li, X | 1 |
| Lian, Q | 1 |
| Huang, P | 1 |
| Ge, RS | 2 |
| Villaseñor, M | 3 |
| Coscioni, AC | 2 |
| Galvão, KN | 2 |
| Chebel, RC | 2 |
| Santos, JE | 3 |
| Ma, X | 1 |
| Lian, QQ | 1 |
| Dong, Q | 1 |
| Velasquez-Pereira, J | 1 |
| Aréchiga, CF | 1 |
| McDowell, LR | 2 |
| Hansen, PJ | 3 |
| Chenoweth, PJ | 2 |
| Calhoun, MC | 2 |
| Risco, CA | 1 |
| Batra, TR | 1 |
| Williams, SN | 1 |
| Wilkinson, NS | 2 |
| Robinson, PH | 1 |
| DePeters, EJ | 1 |
| Holmberg, CA | 1 |
| Jo, C | 1 |
| Yook, HS | 1 |
| Lee, MS | 1 |
| Kim, JH | 1 |
| Song, HP | 1 |
| Kwon, JS | 1 |
| Byun, MW | 1 |
| Hernández-Cerón, J | 1 |
| Jousan, FD | 1 |
| Soto, P | 1 |
| Juchem, SO | 1 |
| Sischo, WM | 1 |
| Xu, Y | 1 |
| Wang, WH | 1 |
| Qian, SZ | 2 |
| Bi, XF | 1 |
| Zheng, YJ | 1 |
| Yang, HF | 1 |
| Zhang, ZR | 1 |
| Wang, ZG | 1 |
| Reddy, RM | 1 |
| Reddy, YD | 1 |
| Reddanna, P | 1 |
| Govindappa, S | 1 |
| Wang, NG | 3 |
| Li, FY | 1 |
| Li, HP | 1 |
| Lei, HP | 2 |
| Guan, MZ | 2 |
| Wu, YM | 1 |
| Chappel, SC | 1 |
| Flickinger, GL | 1 |
| Posinovec, J | 1 |
| Lindsey, TO | 1 |
| Hawkins, GE | 2 |
| Guthrie, LD | 1 |
| Hahn, DW | 1 |
| Rusticus, C | 1 |
| Probst, A | 1 |
| Homm, R | 1 |
| Johnson, AN | 1 |
| Sakesena, SK | 1 |
| Salmonsen, R | 1 |
| Lau, IF | 1 |
| Chang, MC | 2 |
| Gu, Z | 1 |
| Saksena, SK | 1 |
| Willard, ST | 1 |
| Neuendorff, DA | 1 |
| Lewis, AW | 1 |
| Randel, RD | 1 |
| Lin, YC | 5 |
| Sanbuissho, A | 1 |
| Coskun, S | 1 |
| Rikihisa, Y | 3 |
| Gray, ML | 1 |
| Greene, LW | 1 |
| Williams, GL | 1 |
| Colin-Negrete, J | 1 |
| Kiesling, HE | 1 |
| Ross, TT | 1 |
| Smith, JF | 1 |
| Brocas, C | 1 |
| Rivera, RM | 1 |
| Paula-Lopes, FF | 1 |
| Staples, CR | 1 |
| Boning, AJ | 1 |
| Frick, J | 1 |
| Jungwirth, A | 1 |
| Rovan, E | 1 |
| Kalla, N | 1 |
| Gu, ZP | 2 |
| Mao, BY | 1 |
| Wang, YX | 1 |
| Zhang, RA | 1 |
| Tan, YZ | 1 |
| Chen, ZX | 1 |
| Cao, L | 2 |
| You, GD | 1 |
| Segal, SJ | 1 |
| Blom, JH | 1 |
| Lee, KJ | 1 |
| Rinchard, J | 1 |
| Dabrowski, K | 1 |
| Ottobre, J | 1 |
| Chen, Y | 1 |
| Katoh, N | 1 |
| Moh, PP | 1 |
| Li, PK | 1 |
| Darby, MV | 1 |
| Brueggemeier, RW | 1 |
| Kono, H | 2 |
| Yamaguchi, M | 2 |
| Zuspan, FP | 2 |
| Furuhashi, N | 2 |
| Takayama, K | 2 |
| Yajima, A | 2 |
| Chin Lin, Y | 1 |
| Gu, Y | 1 |
| Etindi, RN | 1 |
| Rillema, JA | 1 |
| Li, YF | 1 |
| Booth, GM | 1 |
| Seegmiller, RE | 1 |
| Caulfield, JJ | 1 |
| Bolander, FF | 1 |
| Beaudoin, AR | 2 |
| Hoffer, AP | 1 |
| Agarwal, A | 1 |
| Meltzer, P | 1 |
| Herlihy, P | 1 |
| Naqvi, RH | 2 |
| Lindberg, MC | 2 |
| Matlin, SA | 2 |
| Eisele, GR | 1 |
| Sein, GM | 1 |
| Cummins, KA | 1 |
| Silverio, M | 1 |
| Jilek, JJ | 1 |
| Zhou, R | 1 |
| Bialy, G | 1 |
| Blye, RP | 1 |
| Fukaya, T | 1 |
| Walton, A | 2 |
| Wang, Y | 1 |
| Shi, XQ | 1 |
| Sun, YB | 1 |
| Fishbein, L | 1 |
4 reviews available for gossypol and Pregnancy
| Article | Year |
|---|---|
Environmental inhibitors of 11β-hydroxysteroid dehydrogenase type 2.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Endothelium, Vascular; Epididymis; Female; Glycyrrhiza; | 2011 |
Gossypol: a potential antifertility agent for males.
Topics: Animals; Chemical Phenomena; Chemistry; Chromosome Aberrations; Contraceptive Agents, Male; Embryo, | 1984 |
[A pill for the man? Current status of fertility control in the man].
Topics: Contraceptive Agents, Male; Family Planning Services; Female; Forecasting; Gossypol; Humans; Infant, | 1998 |
Natural non-nutrient substances in the food chain.
Topics: Abnormalities, Drug-Induced; Alkaloids; Animals; Antithyroid Agents; Arsenic Poisoning; Cadmium Pois | 1972 |
1 trial available for gossypol and Pregnancy
| Article | Year |
|---|---|
Low dose gossypol for male contraception.
Topics: Contraceptive Agents, Male; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; | 2000 |
48 other studies available for gossypol and Pregnancy
| Article | Year |
|---|---|
A gossypol derivative effectively protects against Zika and dengue virus infection without toxicity.
Topics: Animals; Cross Reactions; Dengue; Dengue Virus; Female; Gossypol; Male; Mice; Pregnancy; Zika Virus; | 2022 |
Gestational and lactational exposure to gossypol alters the testis transcriptome.
Topics: Animals; Female; Gene Ontology; Gossypol; Lactation; Male; Maternal Exposure; Pregnancy; RNA-Seq; Sh | 2020 |
Neuroinflammation Induction and Alteration of Hippocampal Neurogenesis in Mice Following Developmental Exposure to Gossypol.
Topics: Animals; Animals, Newborn; Behavior, Animal; Cognitive Dysfunction; Disease Models, Animal; Endocrin | 2021 |
Cottonseed (gossypol) intake during gestation and lactation does affect the ovarian population in ewes and lambs?
Topics: Animals; Female; Gossypol; Lactation; Oocytes; Ovary; Pregnancy; Progesterone; Reproduction; Sheep | 2021 |
Mechanisms involved in reproductive damage caused by gossypol in rats and protective effects of vitamin E.
Topics: Animals; Contraceptive Agents, Male; Female; Fertility; Glutathione Peroxidase; Glutathione Reductas | 2015 |
Gossypol enantiomers potently inhibit human placental 3β-hydroxysteroid dehydrogenase 1 and aromatase activities.
Topics: Animals; Aromatase; Aromatase Inhibitors; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Female; | 2016 |
Gossypol disrupts embryo development in heifers.
Topics: Animals; Body Weight; Cattle; Diet; Eating; Embryo Culture Techniques; Embryo, Mammalian; Embryonic | 2008 |
Effects of gossypol from cottonseed meal and dietary vitamin E on the reproductive characteristics of superovulated beef heifers.
Topics: alpha-Tocopherol; Animal Feed; Animals; Cattle; Cottonseed Oil; Dose-Response Relationship, Drug; Em | 2002 |
Type of cottonseed and level of gossypol in diets of lactating dairy cows: plasma gossypol, health, and reproductive performance.
Topics: Abortion, Veterinary; Animals; Cattle; Cattle Diseases; Cottonseed Oil; Diet; Female; Gossypol; Heal | 2003 |
Irradiation effects on embryotoxicity and oxidative properties of gossypol dissolved in methanol.
Topics: Animals; Biphenyl Compounds; Blastocyst; Cell Line; Chromatography, High Pressure Liquid; Dose-Respo | 2003 |
Timing of inhibitory actions of gossypol on cultured bovine embryos.
Topics: Animals; Apoptosis; Cattle; Cell Division; Contraceptive Agents, Male; Embryo, Mammalian; Embryonic | 2005 |
Embryo survival from gossypol-fed heifers after transfer to lactating cows treated with human chorionic gonadotropin.
Topics: Animals; Cattle; Chorionic Gonadotropin; Corpus Luteum; Diet; Embryo Transfer; Embryo, Mammalian; Em | 2006 |
[Antagonism of antifertility effect of gossypol by aspirin].
Topics: Animals; Aspirin; Contraceptive Agents, Male; Female; Fertility; Gossypol; Male; Mice; Pregnancy; Ra | 1983 |
The effect of gossypol on ATPase activity of the kidney.
Topics: Animals; Brain; Female; Fetus; Gossypol; Guinea Pigs; Humans; Kidney; Kinetics; Male; Potassium; Pre | 1981 |
Pattern of ovarian and uterine carbohydrate metabolism during induced antiimplantation by (+)gossypol.
Topics: Animals; Carbohydrate Metabolism; Embryo Implantation; Female; Glycogen; Gossypol; Ovary; Pregnancy; | 1984 |
[Effect of gossypol acetic acid on early pregnancy in rats].
Topics: Animals; Castration; Chorionic Gonadotropin; Contraceptive Agents, Female; Female; Gossypol; Male; O | 1984 |
[Effects of (-) and (+) gossypol on the fertility of male rats].
Topics: Animals; Female; Fertility; Gossypol; Male; Pregnancy; Rats; Rats, Inbred Strains; Spermatozoa; Ster | 1984 |
Effects of gossypol on pituitary-ovarian endocrine function, ovulation and fertility in female hamsters.
Topics: Animals; Body Weight; Cricetinae; Estrogens; Estrus; Female; Fertility; Follicle Stimulating Hormone | 1981 |
[Gossypol - the newest agent for the prevention of male fertility].
Topics: Animals; Contraceptive Agents, Male; Cricetinae; Female; Gossypol; Humans; Male; Pregnancy; Rats | 1983 |
Physiological responses of lactating cows to gossypol from cottonseed meal rations.
Topics: Animal Feed; Animals; Cattle; Cattle Diseases; Erythrocytes; Female; Gossypol; Hematocrit; Hematuria | 1980 |
Antifertility and endocrine activities of gossypol in rodents.
Topics: Animals; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Female; Fertility; Gossypol; | 1981 |
Gossypol: its toxicological and endocrinological effects in male rabbits.
Topics: Animals; Female; Fertility; Gossypol; Male; Organ Size; Pregnancy; Rabbits; Semen; Sperm Count; Test | 1981 |
Effects of Gossypol on the fertility of male rats, hamsters and rabbits.
Topics: Animals; Cricetinae; Embryo Implantation; Female; Fertility; Gossypol; Male; Organ Size; Pregnancy; | 1980 |
Effects of free gossypol in the diet of pregnant and postpartum Brahman cows on calf development and cow performance.
Topics: Acetates; Animals; Animals, Suckling; Blood Urea Nitrogen; Bone Development; Carotenoids; Cattle; Co | 1995 |
Inhibition of in vitro fertilization and early embryonic development in hamsters by gossypol.
Topics: Animals; Cricetinae; Embryo Implantation; Embryonic and Fetal Development; Female; Fertilization in | 1994 |
Effects of dietary gossypol consumption on metabolic homeostasis and reproductive endocrine function in beef heifers and cows.
Topics: Androstenedione; Animal Feed; Animals; Cattle; Endocrine Glands; Estradiol; Estrus; Female; Follicul | 1993 |
[Effect of (+), (-) and (+/-) gossypol on early pregnancy in rats].
Topics: Abortifacient Agents, Nonsteroidal; Animals; Female; Gossypol; Granulosa Cells; Luteal Cells; Pregna | 1996 |
Effect of whole cottonseed on serum constituents, fragility of erythrocyte cells, and reproduction of growing Holstein heifers.
Topics: Animal Feed; Animals; Bilirubin; Blood Glucose; Blood Proteins; Blood Urea Nitrogen; Cattle; Cholest | 1996 |
Deleterious actions of gossypol on bovine spermatozoa, oocytes, and embryos.
Topics: Animals; Cattle; Cells, Cultured; Cottonseed Oil; Diet; Embryo, Mammalian; Erythrocytes; Female; Fer | 1997 |
Reproductive efficiency and maternal-offspring transfer of gossypol in rainbow trout (Oncorhynchus mykiss) fed diets containing cottonseed meal.
Topics: Animals; Cottonseed Oil; Diet; Dietary Proteins; Estradiol; Female; Gossypol; Hemoglobins; Hydroxypr | 2001 |
[Effect of gossypol in combination with misoprostol on termination of early pregnancy in rats and mice].
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Animals; Contraceptive Agents, Female; Decidu | 1997 |
Signal transduction systems mediated by protein kinase-C and estradiol receptors in cow placenta and caruncle.
Topics: Animals; Autoradiography; Cattle; Cell Fractionation; Chromatography, DEAE-Cellulose; Doxorubicin; F | 1992 |
Characteristics of covalent gossypol binding to microsomal proteins.
Topics: Animals; Cattle; Cell Membrane; Chromatography, High Pressure Liquid; Female; Gossypol; Humans; Male | 1992 |
Effects of progesterone and gossypol on monoamine oxidase activity in human term placental explant.
Topics: Female; Gossypol; Humans; Monoamine Oxidase; Organ Culture Techniques; Placenta; Pregnancy; Progeste | 1991 |
Gossypol effects on monoamine oxidase (MAO) activity in several organs of term rats.
Topics: Animals; Female; Fetus; Gossypol; Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Placenta; | 1991 |
Effect of kinase C inhibitor, gossypol, on the actions of prolactin in cultured mouse mammary tissues.
Topics: Animals; Caseins; Cells, Cultured; Female; Gossypol; Kinetics; Lipids; Mammary Glands, Animal; Mice; | 1987 |
Evidence for embryotoxicity of gossypol in mice and chicks with no evidence of mutagenic activity in the Ames test.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Chick Embryo; Embryo, Mammalian; Female; Fetal Re | 1989 |
Involvement of protein kinase C in mouse mammary gland development.
Topics: Animals; Calcimycin; Female; Gossypol; Lactalbumin; Lactation; Mammary Glands, Animal; Mice; Mice, I | 1986 |
A developmental toxicity evaluation of gossypol.
Topics: Animals; Body Weight; Contraceptive Agents, Male; Embryonic and Fetal Development; Female; Fetal Res | 1988 |
Ultrastructural, fertility, and spermicidal studies with isomers and derivatives of gossypol in male hamsters.
Topics: Animals; Cricetinae; Female; Fertility; Gossypol; Humans; Isomerism; Male; Mesocricetus; Pregnancy; | 1987 |
A perspective on gossypol ingestion in swine.
Topics: Animal Feed; Animals; Antidotes; Diet; Female; Glycine max; Gossypol; Pregnancy; Reproduction; Swine | 1986 |
The embryotoxic and immunodepressive effects of gossypol.
Topics: Animals; Antibody Formation; Body Weight; Embryo Implantation; Embryo, Mammalian; Embryonic and Feta | 1986 |
Physiological effects of whole cottonseed in the diet of lactating dairy cows.
Topics: Animal Feed; Animals; Cattle; Cottonseed Oil; Fatty Acids, Unsaturated; Female; Gossypol; Lactation; | 1985 |
(-)-Gossypol: an active male antifertility agent.
Topics: Animals; Contraceptive Agents, Male; Cricetinae; Female; Fertility; Gossypol; Male; Mesocricetus; Pr | 1985 |
Gossypol in female fertility control: ovum implantation and early pregnancy inhibited in rats.
Topics: Animals; Contraceptive Agents, Female; Embryo Implantation; Estradiol; Estrus; Female; Gossypol; Pre | 1985 |
The embryotoxicity of gossypol.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Fetal Resorption; Fetus; Gossypol; | 1985 |
Histopathologic changes of uterus following gossypol treatment during early pregnancy in rats.
Topics: Animals; Female; Gossypol; Microscopy, Electron; Pregnancy; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Antifertility effect of polyvinylpyrrolidone-gossypol and gossypol in male rats.
Topics: Animals; Drug Interactions; Female; Fertility; Gossypol; Male; Povidone; Pregnancy; Rats; Rats, Inbr | 1985 |