gossypol has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 2 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Co-treatment with gossypol acetate and dexamethasone notably amplified the pro-apoptosis activity of the latter in Raji cells." | 1.38 | [Effects of gossypol acetate on apoptosis in primary cultured cells from patients with lymphoid leukemia and its synergy with dexamethasone]. ( Cheng, W; Li, YM; Yang, DJ; Zhao, YQ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spijkers-Hagelstein, JA | 1 |
| Schneider, P | 1 |
| Pinhanços, SM | 1 |
| Garrido Castro, P | 1 |
| Pieters, R | 1 |
| Stam, RW | 1 |
| Cheng, W | 1 |
| Zhao, YQ | 1 |
| Li, YM | 1 |
| Yang, DJ | 1 |
2 other studies available for gossypol and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Glucocorticoid sensitisation in Mixed Lineage Leukaemia-rearranged acute lymphoblastic leukaemia by the pan-BCL-2 family inhibitors gossypol and AT-101.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Dose-Response Relationshi | 2014 |
[Effects of gossypol acetate on apoptosis in primary cultured cells from patients with lymphoid leukemia and its synergy with dexamethasone].
Topics: Apoptosis; Cell Line; Dexamethasone; Gossypol; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Precu | 2012 |