Page last updated: 2024-10-28

gossypol and Necrosis

gossypol has been researched along with Necrosis in 7 studies

Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Gossypol is a phenolic aldehyde extracted from plants and is known to be an antitumor agent to induce cancer cell apoptosis."5.40Proteomic analysis of gossypol induces necrosis in multiple myeloma cells. ( Liu, C; Tang, H; Tian, E; Wang, Q; Xu, R, 2014)
"Gossypol is a phenolic aldehyde extracted from plants and is known to be an antitumor agent to induce cancer cell apoptosis."1.40Proteomic analysis of gossypol induces necrosis in multiple myeloma cells. ( Liu, C; Tang, H; Tian, E; Wang, Q; Xu, R, 2014)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Zhong, M1
Huang, Y1
Zeng, B1
Xu, L1
Zhong, C1
Qiu, J1
Ye, X1
Chen, M1
Hu, B1
Ouyang, D1
He, X1
Tang, H2
Tian, E2
Liu, C2
Wang, Q2
Deng, H1
Xu, R1
Hanus, J1
Zhang, H1
Chen, DH1
Zhou, Q1
Jin, P1
Liu, Q1
Wang, S1
Deoras, DP1
Young-Curtis, P1
Dalvi, RR1
Tippett, FE1
Velasquez-Pereira, J1
Risco, CA1
McDowell, LR1
Staples, CR1
Prichard, D1
Chenoweth, PJ1
Martin, FG1
Williams, SN1
Rojas, LX1
Calhoun, MC1
Wilkinson, NS1
Holmberg, CA1
Weaver, LD1
Guterbock, WM1
Genes, J1
Montgomery, P1

Other Studies

7 other studies available for gossypol and Necrosis

ArticleYear
Induction of multiple subroutines of regulated necrosis in murine macrophages by natural BH3-mimetic gossypol.
    Acta biochimica et biophysica Sinica, 2022, 01-25, Volume: 54, Issue:1

    Topics: Animals; Apoptosis; Caspase 1; Gossypol; Inflammasomes; Macrophages; Mice; Mice, Inbred C57BL; Necro

2022
Oxidative stress induces monocyte necrosis with enrichment of cell-bound albumin and overexpression of endoplasmic reticulum and mitochondrial chaperones.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Amino Acid Sequence; Animals; Apoptosis; Azacitidine; Cattle; Cell Line; Culture Media; Endoplasmic

2013
Proteomic analysis of gossypol induces necrosis in multiple myeloma cells.
    BioMed research international, 2014, Volume: 2014

    Topics: Blotting, Western; Cell Line, Tumor; Cell Shape; Electrophoresis, Polyacrylamide Gel; Gossypol; Huma

2014
Gossypol Acetic Acid Prevents Oxidative Stress-Induced Retinal Pigment Epithelial Necrosis by Regulating the FoxO3/Sestrin2 Pathway.
    Molecular and cellular biology, 2015, Jun-01, Volume: 35, Issue:11

    Topics: Antioxidants; Cell Death; Cell Line; Cell Survival; Forkhead Box Protein O3; Forkhead Transcription

2015
Effect of gossypol on hepatic and serum gamma-glutamyltransferase activity in rats.
    Veterinary research communications, 1997, Volume: 21, Issue:5

    Topics: Aminopyrine N-Demethylase; Animal Feed; Animals; Cytochrome P-450 Enzyme System; gamma-Glutamyltrans

1997
Long-term effects of feeding gossypol and vitamin E to dairy calves.
    Journal of dairy science, 1999, Volume: 82, Issue:6

    Topics: Animal Feed; Animals; Atrophy; Cattle; Cattle Diseases; Gossypol; Hematocrit; Hemoglobins; Liver; Ma

1999
Pathological and toxicological studies of calves fed a high concentration cotton seed meal diet.
    Veterinary pathology, 1988, Volume: 25, Issue:2

    Topics: Animal Feed; Animals; Cattle; Cattle Diseases; Cottonseed Oil; Disease Outbreaks; Edema; Gossypol; H

1988