gossypol has been researched along with Nasopharyngeal Carcinoma in 2 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Nasopharyngeal Carcinoma: A carcinoma that originates in the EPITHELIUM of the NASOPHARYNX and includes four subtypes: keratinizing squamous cell, non-keratinizing, basaloid squamous cell, and PAPILLARY ADENOCARCINOMA. It is most prevalent in Southeast Asian populations and is associated with EPSTEIN-BARR VIRUS INFECTIONS. Somatic mutations associated with this cancer have been identified in NPCR, BAP1, UBAP1, ERBB2, ERBB3, MLL2, PIK3CA, KRAS, NRAS, and ARID1A genes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gossypol has been reported to exhibit antitumor effects against several human cancers." | 5.62 | Bioinformatics Analysis of the Signaling Pathways and Genes of Gossypol Induce Death of Nasopharyngeal Carcinoma Cells. ( Ge, J; Gong, Z; He, Y; Huang, W; Jiang, X; Li, P; Mo, Y; Wang, J; Xiong, W; Yu, J; Zeng, Z; Zhu, K, 2021) |
| "Gossypol has been reported to exhibit antitumor effects against several human cancers." | 1.62 | Bioinformatics Analysis of the Signaling Pathways and Genes of Gossypol Induce Death of Nasopharyngeal Carcinoma Cells. ( Ge, J; Gong, Z; He, Y; Huang, W; Jiang, X; Li, P; Mo, Y; Wang, J; Xiong, W; Yu, J; Zeng, Z; Zhu, K, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, K | 1 |
| Ge, J | 1 |
| He, Y | 1 |
| Li, P | 1 |
| Jiang, X | 1 |
| Wang, J | 1 |
| Mo, Y | 1 |
| Huang, W | 1 |
| Gong, Z | 1 |
| Zeng, Z | 1 |
| Xiong, W | 1 |
| Yu, J | 1 |
| He, JH | 1 |
| Liao, XL | 1 |
| Wang, W | 1 |
| Li, DD | 1 |
| Chen, WD | 1 |
| Deng, R | 1 |
| Yang, D | 1 |
| Han, ZP | 1 |
| Jiang, JW | 1 |
| Zhu, XF | 1 |
2 other studies available for gossypol and Nasopharyngeal Carcinoma
| Article | Year |
|---|---|
Bioinformatics Analysis of the Signaling Pathways and Genes of Gossypol Induce Death of Nasopharyngeal Carcinoma Cells.
Topics: Antineoplastic Agents; Cell Cycle Proteins; Cell Death; Cell Line, Tumor; Drug Resistance, Neoplasm; | 2021 |
Apogossypolone, a small-molecule inhibitor of Bcl-2, induces radiosensitization of nasopharyngeal carcinoma cells by stimulating autophagy.
Topics: Animals; Autophagy; Carcinoma; Cell Line, Tumor; Cell Proliferation; Chemoradiotherapy; Dose-Respons | 2014 |