gossypol has been researched along with Invasiveness, Neoplasm in 4 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gossypol is a natural polyphenolic compound with anti-inflammation, anti-oxidant, and anticancer activities." | 1.62 | Gossypol Reduces Metastasis and Epithelial-Mesenchymal Transition by Targeting Protease in Human Cervical Cancer. ( Chen, PN; Chu, SC; Hsieh, YS; Huang, SC; Kao, SH; Lin, MS, 2021) |
| "Targeted approaches for treating glioblastoma (GBM) attempted to date have consistently failed, highlighting the imperative for treatment strategies that operate on different mechanistic principles." | 1.48 | Regulation of bioenergetics through dual inhibition of aldehyde dehydrogenase and mitochondrial complex I suppresses glioblastoma tumorspheres. ( Chang, JH; Choi, J; Kang, JH; Kang, SG; Kim, SY; Park, J; Shim, JK, 2018) |
| "Acquisition of metastatic ability by prostatic cancer cells is the most lethal aspect of prostatic cancer progression." | 1.35 | (-)-Gossypol reduces invasiveness in metastatic prostate cancer cells. ( Dowd, MK; Huang, YW; Lin, YC; Wan, PJ; Wang, LS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsieh, YS | 1 |
| Chu, SC | 1 |
| Huang, SC | 1 |
| Kao, SH | 1 |
| Lin, MS | 1 |
| Chen, PN | 1 |
| Park, J | 1 |
| Shim, JK | 1 |
| Kang, JH | 1 |
| Choi, J | 1 |
| Chang, JH | 1 |
| Kim, SY | 1 |
| Kang, SG | 1 |
| Huang, YW | 1 |
| Wang, LS | 1 |
| Dowd, MK | 1 |
| Wan, PJ | 1 |
| Lin, YC | 1 |
| Jiang, J | 1 |
| Slivova, V | 1 |
| Jedinak, A | 1 |
| Sliva, D | 1 |
4 other studies available for gossypol and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Gossypol Reduces Metastasis and Epithelial-Mesenchymal Transition by Targeting Protease in Human Cervical Cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Movement; Disease Models, Animal; Epithelial-Mesenc | 2021 |
Regulation of bioenergetics through dual inhibition of aldehyde dehydrogenase and mitochondrial complex I suppresses glioblastoma tumorspheres.
Topics: Adenosine Triphosphate; Aldehyde Dehydrogenase; Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Pr | 2018 |
(-)-Gossypol reduces invasiveness in metastatic prostate cancer cells.
Topics: Animals; Apoptosis; bcl-X Protein; Blotting, Western; Cell Movement; Cell Proliferation; Contracepti | 2009 |
Gossypol inhibits growth, invasiveness, and angiogenesis in human prostate cancer cells by modulating NF-κB/AP-1 dependent- and independent-signaling.
Topics: Cell Division; Cell Line, Tumor; Electrophoretic Mobility Shift Assay; G1 Phase; Gossypol; Humans; I | 2012 |