gossypol has been researched along with Granulocytic Leukemia, Chronic in 2 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gossypol is a natural polyphenolic compound isolated from cottonseed and has antiproliferative activity in a variety of cancer cell lines." | 1.34 | (-)Gossypol and its combination with imatinib induce apoptosis in human chronic myeloid leukemic cells. ( Chen, X; Fu, J; Li, H; Li, J; Li, Y; Liu, H; Liu, Y; Meng, Y, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ergun, MA | 1 |
| Konac, E | 1 |
| Erbas, D | 1 |
| Ekmekci, A | 1 |
| Meng, Y | 1 |
| Li, Y | 1 |
| Li, J | 1 |
| Li, H | 1 |
| Fu, J | 1 |
| Liu, Y | 1 |
| Liu, H | 1 |
| Chen, X | 1 |
2 other studies available for gossypol and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Apoptosis and nitric oxide release induced by thalidomide, gossypol and dexamethasone in cultured human chronic myelogenous leukemic K-562 cells.
Topics: Apoptosis; Contraceptive Agents, Male; Dexamethasone; Dose-Response Relationship, Drug; Glucocortico | 2004 |
(-)Gossypol and its combination with imatinib induce apoptosis in human chronic myeloid leukemic cells.
Topics: Apoptosis; bcl-X Protein; Benzamides; Caspase 3; Cell Proliferation; Cytochromes c; Down-Regulation; | 2007 |