Page last updated: 2024-10-28

gossypol and Germinoblastoma

gossypol has been researched along with Germinoblastoma in 7 studies

Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.

Research Excerpts

ExcerptRelevanceReference
"We examined the effect of apogossypolone (ApoG2), a new derivative from gossypol on cell cycle regulation in U937 human leukemic monocyte lymphoma cells in vitro."3.75Apogossypolone inhibits cell growth by inducing cell cycle arrest in U937 cells. ( Hu, ZY; Jiang, WQ; Li, ZM; Sun, J; Yang, DJ; Zeng, ZL, 2009)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johnson, PW1
Azmi, AS1
Mohammad, RM1
Wei, J1
Kitada, S1
Rega, MF1
Emdadi, A1
Yuan, H1
Cellitti, J1
Stebbins, JL1
Zhai, D1
Sun, J2
Yang, L1
Dahl, R1
Zhang, Z1
Wu, B1
Wang, S1
Reed, TA1
Wang, HG1
Lawrence, N1
Sebti, S1
Reed, JC1
Pellecchia, M1
Li, ZM1
Hu, ZY1
Zeng, ZL1
Yang, DJ1
Jiang, WQ1
Sylvester, PW1
Ip, MM1
Briski, KP1
Rillema, JA1
Waters, SB1
Tarrant, TM1
Russell, DH1
Buckley, AR1
Montgomery, DW1
Larson, NA1
Gout, PW1
Beer, CT1
Putnam, CW1
Zukoski, CF1
Kibler, R1

Reviews

2 reviews available for gossypol and Germinoblastoma

ArticleYear
New targets for lymphoma treatment.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19 Suppl 4

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Clinical Trials, Phase II as Topic; Enzyme

2008
Non-peptidic small molecule inhibitors against Bcl-2 for cancer therapy.
    Journal of cellular physiology, 2009, Volume: 218, Issue:1

    Topics: Aniline Compounds; Animals; Apoptosis; Benzamides; Binding Sites; Biphenyl Compounds; Gossypol; Huma

2009

Other Studies

5 other studies available for gossypol and Germinoblastoma

ArticleYear
Apogossypol derivatives as antagonists of antiapoptotic Bcl-2 family proteins.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:4

    Topics: Animals; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated

2009
Apogossypolone inhibits cell growth by inducing cell cycle arrest in U937 cells.
    Oncology reports, 2009, Volume: 22, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Proliferation; Cell Survival; Cyclin D

2009
Effects of specific fatty acids on prolactin-induced NB2 lymphoma cell proliferation.
    Life sciences, 1993, Volume: 52, Issue:24

    Topics: Animals; Arachidonic Acid; Cell Division; Cell Line; Dose-Response Relationship, Drug; Fatty Acids;

1993
Studies on the possible role of protein kinase C in the prolactin regulation of cell replication in Nb2 node lymphoma cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1989, Volume: 192, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Division; Cell Line; Gossypol; Isoquino

1989
Prolactin-dependent mitogenesis in Nb 2 node lymphoma cells: effects of immunosuppressive cyclopeptides.
    Journal of immunology (Baltimore, Md. : 1950), 1987, Jan-01, Volume: 138, Issue:1

    Topics: Animals; Calcimycin; Cell Division; Cyclosporins; Depsipeptides; DNA; Enzyme Induction; Estradiol; G

1987