gossypol has been researched along with Experimental Neoplasms in 11 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study has evaluated the chemopreventive effects of gossypol on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastric carcinogenesis and on human gastric adenocarcinoma (AGS) cell line." | 7.77 | In vitro and in vivo studies on antitumor effects of gossypol on human stomach adenocarcinoma (AGS) cell line and MNNG induced experimental gastric cancer. ( Gayathri, R; Gunassekaran, GR; Priya, DK; Sakthisekaran, D, 2011) |
| "5/3-mda-7 alone or in combination with BI-97C1 would be predicted to exert significantly improved therapeutic efficacy in colorectal cancer patients." | 5.38 | Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells. ( Azab, B; Bhutia, SK; Curiel, DT; Das, SK; Dash, R; Dent, P; Dmitriev, IP; Fisher, PB; Grant, S; Hedvat, M; Pellecchia, M; Quinn, BA; Reed, JC; Sarkar, D; Sarkar, S; Shen, XN; Wang, XY, 2012) |
| "The present study has evaluated the chemopreventive effects of gossypol on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastric carcinogenesis and on human gastric adenocarcinoma (AGS) cell line." | 3.77 | In vitro and in vivo studies on antitumor effects of gossypol on human stomach adenocarcinoma (AGS) cell line and MNNG induced experimental gastric cancer. ( Gayathri, R; Gunassekaran, GR; Priya, DK; Sakthisekaran, D, 2011) |
| "5/3-mda-7 alone or in combination with BI-97C1 would be predicted to exert significantly improved therapeutic efficacy in colorectal cancer patients." | 1.38 | Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells. ( Azab, B; Bhutia, SK; Curiel, DT; Das, SK; Dash, R; Dent, P; Dmitriev, IP; Fisher, PB; Grant, S; Hedvat, M; Pellecchia, M; Quinn, BA; Reed, JC; Sarkar, D; Sarkar, S; Shen, XN; Wang, XY, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (45.45) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| He, JH | 1 |
| Liao, XL | 1 |
| Wang, W | 1 |
| Li, DD | 1 |
| Chen, WD | 1 |
| Deng, R | 1 |
| Yang, D | 1 |
| Han, ZP | 1 |
| Jiang, JW | 1 |
| Zhu, XF | 1 |
| Tomoda, K | 1 |
| Chiang, HC | 1 |
| Kozak, KR | 1 |
| Kwon, GS | 1 |
| Azab, B | 1 |
| Dash, R | 1 |
| Das, SK | 1 |
| Bhutia, SK | 1 |
| Shen, XN | 1 |
| Quinn, BA | 1 |
| Sarkar, S | 1 |
| Wang, XY | 1 |
| Hedvat, M | 1 |
| Dmitriev, IP | 1 |
| Curiel, DT | 1 |
| Grant, S | 1 |
| Dent, P | 1 |
| Reed, JC | 1 |
| Pellecchia, M | 1 |
| Sarkar, D | 1 |
| Fisher, PB | 1 |
| Gunassekaran, GR | 1 |
| Priya, DK | 1 |
| Gayathri, R | 1 |
| Sakthisekaran, D | 1 |
| VERMEL, EM | 2 |
| KRUGLIAK, SA | 1 |
| Lei, X | 1 |
| Chen, Y | 1 |
| Du, G | 1 |
| Yu, W | 1 |
| Wang, X | 1 |
| Qu, H | 1 |
| Xia, B | 1 |
| He, H | 1 |
| Mao, J | 1 |
| Zong, W | 1 |
| Liao, X | 1 |
| Mehrpour, M | 1 |
| Hao, X | 1 |
| Chen, Q | 1 |
| Benz, CC | 1 |
| Iyer, SB | 1 |
| Asgari, HS | 1 |
| Matlin, SA | 1 |
| Aronson, FR | 1 |
| Barchowsky, A | 1 |
| Rao, PN | 1 |
| Wang, YC | 1 |
| Lotzova, E | 1 |
| Khan, AA | 1 |
| Rao, SP | 1 |
| Stephens, LC | 1 |
| Sinnhuber, RO | 1 |
| Lee, DJ | 1 |
| Wales, JH | 1 |
| Ayres, JL | 1 |
| Ghittino, P | 1 |
| Provana, A | 1 |
| Codegone, ML | 1 |
11 other studies available for gossypol and Experimental Neoplasms
| Article | Year |
|---|---|
Apogossypolone, a small-molecule inhibitor of Bcl-2, induces radiosensitization of nasopharyngeal carcinoma cells by stimulating autophagy.
Topics: Animals; Autophagy; Carcinoma; Cell Line, Tumor; Cell Proliferation; Chemoradiotherapy; Dose-Respons | 2014 |
Injectable (-)-gossypol-loaded Pluronic P85 micelles for cancer chemoradiotherapy.
Topics: A549 Cells; Animals; Antineoplastic Agents; Cell Survival; Chemoradiotherapy; Dose-Response Relation | 2017 |
Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells.
Topics: Adenoviridae; Animals; Cell Line, Tumor; Colorectal Neoplasms; Coxsackie and Adenovirus Receptor-Lik | 2012 |
In vitro and in vivo studies on antitumor effects of gossypol on human stomach adenocarcinoma (AGS) cell line and MNNG induced experimental gastric cancer.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; | 2011 |
[ANTINEOPLASTIC ACTIVITY OF GOSSYPOL IN EXPERIMENTAL TRANSPLANTED TUMORS].
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatoce | 1963 |
THE SEARCH FOR ANTITUMOUR SUBSTANCES OF PLANT ORIGIN.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Coumarins; Gossypol; Melanoma; Mice; Neopl | 1964 |
Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Cytochromes c; | 2006 |
Gossypol effects on endothelial cells and tumor blood flow.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Blood Flow Velocity; Endothelium, Vascular; | 1991 |
Antitumor effects of gossypol on murine tumors.
Topics: Animals; Cell Count; Drug Administration Schedule; Drug Evaluation; Female; Gossypol; Leukemia L1210 | 1985 |
Dietary factors and hepatoma in rainbow trout (Salmo gairdneri). II. Cocarcinogenes by cyclopropenoid fatty acids and the effect of gossypol and altered lipids on aflatoxin-induced liver cancer.
Topics: Aflatoxins; Animal Feed; Animals; Carcinogens; Carcinoma, Hepatocellular; Coumarins; Fatty Acids; Go | 1968 |
Experimental dietary hepatoma in rainbow trout. The role of cottonseed meals and other diets.
Topics: Acetates; Aflatoxins; Animals; Arachis; Caprylates; Carcinogens; Carcinoma, Hepatocellular; Cottonse | 1967 |