gossypol has been researched along with Experimental Leukemia in 3 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gossypol treatments inhibited cell multiplication at 10 and 20 micrograms/ml concentrations and this inhibitory effect increased with elevated dosage and prolonged treatment." | 1.28 | Genotoxic effects of gossypol acetic acid on cultured murine erythroleukemia cells. ( Baker, MA; Daehler, CC; Daly, EP; Kleemeyer, KM; Majumdar, SK, 1991) |
| "(-)-Gossypol was 3." | 1.28 | Antiproliferative effect of gossypol and its optical isomers on human reproductive cancer cell lines. ( Anderson, DJ; Band, H; Band, V; Hoffer, AP; Knapp, RC; Matlin, SA; Rhinehardt, AE, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jolad, SD | 1 |
| Wiedhopf, RM | 1 |
| Cole, JR | 1 |
| Majumdar, SK | 1 |
| Daly, EP | 1 |
| Kleemeyer, KM | 1 |
| Daehler, CC | 1 |
| Baker, MA | 1 |
| Band, V | 1 |
| Hoffer, AP | 1 |
| Band, H | 1 |
| Rhinehardt, AE | 1 |
| Knapp, RC | 1 |
| Matlin, SA | 1 |
| Anderson, DJ | 1 |
3 other studies available for gossypol and Experimental Leukemia
| Article | Year |
|---|---|
Tumor-inhibitory agent from Montezuma speciosissima (Malvaceae).
Topics: Animals; Antineoplastic Agents; Gossypol; Leukemia, Experimental; Mice; Plants | 1975 |
Genotoxic effects of gossypol acetic acid on cultured murine erythroleukemia cells.
Topics: Animals; Cell Division; Cell Membrane; Chromosome Aberrations; DNA Damage; DNA Replication; Gossypol | 1991 |
Antiproliferative effect of gossypol and its optical isomers on human reproductive cancer cell lines.
Topics: Antineoplastic Agents; Cell Division; Cell Line; DNA, Neoplasm; Dose-Response Relationship, Drug; Fe | 1989 |