gossypol has been researched along with Esophageal Neoplasms in 3 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Esophageal Neoplasms: Tumors or cancer of the ESOPHAGUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gastro-oesophageal cancers (GEC) are resistant to therapy and lead to poor prognosis." | 3.01 | Targeting cancer stem cells with a pan-BCL-2 inhibitor in preclinical and clinical settings in patients with gastroesophageal carcinoma. ( Ajani, JA; Bhutani, M; Chen, Q; Correa, A; Estrella, JS; Gan, B; Hofstetter, WL; Huo, L; Jin, J; Johnson, RL; Lee, JH; Lei, G; Li, CY; Li, Y; Liu, B; Ma, L; Pizzi, MP; Scott, A; Shanbhag, N; Song, S; Wang, Y; Wei, S; Weston, B; Xiao, L, 2021) |
| "Two human breast carcinoma cell lines (MCF-7, MCF-7 Adr) and a rat esophageal cancer cell line (RE-B2T) were used to evaluate the antiproliferative potential of gossypol (GP)-containing milk (GP-Milk), which was collected from Brown Swiss dairy cows treated daily with federally allowable 450 ppm of GP for 6 days." | 1.29 | Presence of antitumor activities in the milk collected from gossypol-treated dairy cows. ( Brueggemeier, RW; Chang, CJ; Hu, YF; Lin, YC, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Song, S | 1 |
| Chen, Q | 1 |
| Li, Y | 1 |
| Lei, G | 1 |
| Scott, A | 1 |
| Huo, L | 1 |
| Li, CY | 1 |
| Estrella, JS | 1 |
| Correa, A | 1 |
| Pizzi, MP | 1 |
| Ma, L | 1 |
| Jin, J | 1 |
| Liu, B | 1 |
| Wang, Y | 1 |
| Xiao, L | 1 |
| Hofstetter, WL | 1 |
| Lee, JH | 1 |
| Weston, B | 1 |
| Bhutani, M | 1 |
| Shanbhag, N | 1 |
| Johnson, RL | 1 |
| Gan, B | 1 |
| Wei, S | 1 |
| Ajani, JA | 1 |
| Yeow, WS | 1 |
| Baras, A | 1 |
| Chua, A | 1 |
| Nguyen, DM | 2 |
| Sehgal, SS | 1 |
| Schrump, DS | 1 |
| Hu, YF | 1 |
| Chang, CJ | 1 |
| Brueggemeier, RW | 1 |
| Lin, YC | 1 |
1 trial available for gossypol and Esophageal Neoplasms
| Article | Year |
|---|---|
Targeting cancer stem cells with a pan-BCL-2 inhibitor in preclinical and clinical settings in patients with gastroesophageal carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Doc | 2021 |
2 other studies available for gossypol and Esophageal Neoplasms
| Article | Year |
|---|---|
Gossypol, a phytochemical with BH3-mimetic property, sensitizes cultured thoracic cancer cells to Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Death; Esophageal Neoplasms; Gossypol; Humans; Lung | 2006 |
Presence of antitumor activities in the milk collected from gossypol-treated dairy cows.
Topics: Animals; Breast Neoplasms; Cattle; Cell Division; Dose-Response Relationship, Drug; Esophageal Neopl | 1994 |