gossypol has been researched along with Endometrioma in 16 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Endometrioma: An enlarged area of ENDOMETRIOSIS that resembles a tumor. It is usually found in the OVARY. When it is filled with old blood, it is known as a chocolate cyst.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the anti-proliferative activity and mitochondrial toxicity of gossypol in endometrioma cells maintained in short-term cultures." | 7.74 | Gossypol inhibits proliferation of endometrioma cells in culture. ( Badawy, SZ; Cuenca, V; Montalto, N; Shue, F; Souid, AK, 2007) |
| "Effects of the gossypol on endometriosis in 12 cases of control were observed." | 7.67 | [Clinical effects and experimental study on gossypol in endometriosis]. ( Wang, M; Xu, LF; Zhao, CL, 1989) |
| "To evaluate the anti-proliferative activity and mitochondrial toxicity of gossypol in endometrioma cells maintained in short-term cultures." | 3.74 | Gossypol inhibits proliferation of endometrioma cells in culture. ( Badawy, SZ; Cuenca, V; Montalto, N; Shue, F; Souid, AK, 2007) |
| "In order to evaluate the drugs in treating endometriosis, the direct effects of gossypol acetate, danazol, progesterone, and gonadotropin releasing hormone-agonist (GnRH-A) on the isolated human endometrial cells were determined by DCC assay." | 3.69 | [Effects of gossypol acetate, danazol, progesterone and GnRH-A on estrogen and progesterone receptors of human endometrial cells]. ( Huang, HF; Wang, M, 1994) |
| "Gossypol treatment of endometriosis and uterine myomas in 15 cases was started with a daily dose of 20 mg of gossypol-acetic acid twice a day for 20 days as a loading dose, followed by 40 mg (20 mg twice weekly)." | 3.67 | Electron microscopic observations of the effects of gossypol on the human endometrium. ( Cheng, J; Dang, MY; Han, ML; Sun, YT; Tian, L; Zu, PD, 1984) |
| "Effects of the gossypol on endometriosis in 12 cases of control were observed." | 3.67 | [Clinical effects and experimental study on gossypol in endometriosis]. ( Wang, M; Xu, LF; Zhao, CL, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (68.75) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Badawy, SZ | 1 |
| Souid, AK | 1 |
| Cuenca, V | 1 |
| Montalto, N | 1 |
| Shue, F | 1 |
| Han, ML | 6 |
| Wang, YF | 6 |
| Ma, XH | 2 |
| Han, HL | 1 |
| Zu, PD | 1 |
| Sun, YT | 2 |
| Cheng, J | 1 |
| Tian, L | 1 |
| Dang, MY | 1 |
| Cheng, KF | 1 |
| Wu, WY | 1 |
| Tang, MY | 2 |
| Chu, PT | 1 |
| Huang, HF | 2 |
| Wang, M | 3 |
| Zhang, YW | 1 |
| Zhang, Y | 1 |
| Wang, Y | 1 |
| Li, C | 1 |
| Zhou, J | 1 |
| Zhang, D | 1 |
| Han, M | 1 |
| Xu, LF | 1 |
| Zhao, CL | 1 |
| Ge, QS | 2 |
| Zhou, LF | 1 |
| Zhu, PD | 1 |
| Ye, XQ | 1 |
| Zhao, Y | 1 |
| Zhang, JC | 1 |
| Ye, LZ | 1 |
| Ma, SW | 1 |
| Luo, HY | 1 |
16 other studies available for gossypol and Endometrioma
| Article | Year |
|---|---|
Gossypol inhibits proliferation of endometrioma cells in culture.
Topics: Cell Line, Tumor; Cell Proliferation; Cell Respiration; Cell Survival; Contraceptive Agents, Male; C | 2007 |
[Clinical observation of the gossypol treatment of endometriosis and uterine myoma and the location of the pharmacological action].
Topics: Adult; Endometriosis; Endometrium; Female; Gonadotropins, Pituitary; Gossypol; Humans; Leiomyoma; Mi | 1982 |
[A comparative study on rapid and slow loading of gossypol in the treatment of gynecological diseases].
Topics: Adult; Endometriosis; Female; Gossypol; Humans; Leiomyoma; Middle Aged; Ovary; Uterine Neoplasms | 1984 |
[Gossypol treatment for menopausal functional bleeding, myoma of uterus and endometriosis--preliminary report (author's transl)].
Topics: Adult; Endometriosis; Female; Gossypol; Humans; Leiomyoma; Menopause; Middle Aged; Uterine Hemorrhag | 1980 |
Electron microscopic observations of the effects of gossypol on the human endometrium.
Topics: Endocrine Glands; Endometriosis; Endometrium; Female; Gossypol; Humans; Leiomyoma; Menstruation; Tim | 1984 |
Endometrial changes after administration of gossypol for menorrhagia.
Topics: Adult; Atrophy; Endometriosis; Endometrium; Female; Gossypol; Humans; Leiomyoma; Menorrhagia; Middle | 1980 |
[Effects of gossypol acetate, danazol, progesterone and GnRH-A on estrogen and progesterone receptors of human endometrial cells].
Topics: Adult; Cells, Cultured; Danazol; Endometriosis; Endometrium; Female; Gonadotropin-Releasing Hormone; | 1994 |
[Estrogen and progesterone cytosol receptor concentrations in patients with endometriosis and their changes after gossypol therapy].
Topics: Adult; Antineoplastic Agents, Phytogenic; Endometriosis; Endometrium; Estradiol; Female; Gossypol; H | 1994 |
Estrogen and progestin cytosol receptor concentrations in patients with endometriosis and their changes after gossypol therapy.
Topics: Endometriosis; Endometrium; Female; Gossypol; Humans; Receptors, Estrogen; Receptors, Progesterone; | 1996 |
[Effects of gossypol and GnRHa on the prostaglandins contents of endometriotic cell and in situ].
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Endometriosis; Endometrium; Female; Gonadotropin-Releasing Horm | 1991 |
[Clinical effects and experimental study on gossypol in endometriosis].
Topics: Adult; Antineoplastic Agents, Phytogenic; Drugs, Chinese Herbal; Endometriosis; Female; Gossypol; Hu | 1989 |
[Observation on blood biochemical indices after gossypol treatment in gynecological cases].
Topics: Adult; Cholesterol; Endometriosis; Female; Gossypol; Humans; Leiomyoma; Lipoproteins, HDL; Middle Ag | 1988 |
Gossypol in the treatment of endometriosis and uterine myoma.
Topics: Adult; Endometriosis; Female; Follicle Stimulating Hormone; Follow-Up Studies; Gossypol; Humans; Lei | 1987 |
[Late effect of gossypol treatment in gynecological diseases--a clinical study of 72 cases].
Topics: Adult; Endometriosis; Female; Follow-Up Studies; Gossypol; Humans; Leiomyoma; Medicine, Chinese Trad | 1985 |
[Clinical and experimental study of gossypol in the treatment of dysfunctional menorrhagia, endometriosis and fibromyoma of the uterus].
Topics: Adult; Aged; Animals; Endometriosis; Female; Gossypol; Humans; Leiomyoma; Menorrhagia; Middle Aged; | 1988 |
Studies on frequencies of sister chromatid exchange in peripheral blood lymphocytes before and after gossypol treatment.
Topics: Adult; Endometriosis; Female; Gossypol; Humans; Leiomyoma; Lymphocytes; Middle Aged; Sister Chromati | 1986 |