gossypol has been researched along with Disease Models, Animal in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 6 (31.58) | 24.3611 |
| 2020's | 5 (26.32) | 2.80 |
| Authors | Studies |
|---|---|
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Lv, X; Shi, X; Xiao, D | 1 |
| Chai, X; Chen, Z; Cui, E; Huang, J; Li, C; Pan, J; Wu, Y; Zhao, S; Zhou, W; Zhu, X | 1 |
| Chen, PN; Chu, SC; Hsieh, YS; Huang, SC; Kao, SH; Lin, MS | 1 |
| Ajani, JA; Bhutani, M; Chen, Q; Correa, A; Estrella, JS; Gan, B; Hofstetter, WL; Huo, L; Jin, J; Johnson, RL; Lee, JH; Lei, G; Li, CY; Li, Y; Liu, B; Ma, L; Pizzi, MP; Scott, A; Shanbhag, N; Song, S; Wang, Y; Wei, S; Weston, B; Xiao, L | 1 |
| Chen, C; Hu, J; Liang, J; Liu, H; Liu, X; Zhao, H | 1 |
| An, Q; Hu, X; Huang, X; Liu, Z; Mu, S; Zhan, Y; Zhang, X | 1 |
| Li, J; Su, T; Wang, J; Xiong, J; Yang, Q; Zhou, S | 1 |
| Semon, B | 1 |
| Chi, G; Cui, X; Deng, X; Duan, L; Feng, H; Gao, R; Guan, S; Huo, M; Jiang, L; Soromou, LW; Wei, J | 1 |
| Alhonen, L; Herzig, KH; Jänne, J; Kaasinen, K; Keinänen, T; Räsänen, TL; Sinervirta, R; Uimari, A | 1 |
| Susman, E | 1 |
| Gardner, JR; Gonen, M; Heaney, ML; Holmlund, J; Leopold, L; Manova, K; Marcucci, G; Mastrella, J; O'Connor, OA; Paoluzzi, L; Sorensen, M; Yang, D | 1 |
| Brueggemeier, RW; Canatan, H; Chang, CJ; Chang, WY; Kulp, SK; Lin, YC; Shidaifat, F; Sugimoto, Y | 1 |
| Chan, HC; Yu, ZH | 1 |
| Abe, Y; Arakawa, Y; Itoh, K | 1 |
| Bostwick, JS; Decktor, DL; Fitzpatrick, LR; Pendleton, RG; Renzetti, M | 1 |
| Goriunova, LV; Oĭfa, AI; Vichkanova, SA | 1 |
1 review(s) available for gossypol and Disease Models, Animal
| Article | Year |
|---|---|
Gossypol as a male antifertility agent--why studies should have been continued.
Topics: Animals; beta 2-Microglobulin; Contraceptive Agents, Male; Disease Models, Animal; Gossypol; Humans; Hypokalemia; Male; Oligospermia; Research | 1998 |
1 trial(s) available for gossypol and Disease Models, Animal
| Article | Year |
|---|---|
Targeting cancer stem cells with a pan-BCL-2 inhibitor in preclinical and clinical settings in patients with gastroesophageal carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Docetaxel; Esophageal Neoplasms; Female; Gossypol; Humans; Male; Mice; Middle Aged; Neoplastic Stem Cells; Pilot Projects; Proto-Oncogene Proteins c-bcl-2; Stomach Neoplasms | 2021 |
17 other study(ies) available for gossypol and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Gossypol improves myocardial dysfunction caused by sepsis by regulating histone acetylation.
Topics: Acetylation; Animals; Cytokines; Disease Models, Animal; Gossypol; Histones; Lipopolysaccharides; Mice; Proto-Oncogene Proteins c-akt; Sepsis | 2023 |
Neuroinflammation Induction and Alteration of Hippocampal Neurogenesis in Mice Following Developmental Exposure to Gossypol.
Topics: Animals; Animals, Newborn; Behavior, Animal; Cognitive Dysfunction; Disease Models, Animal; Endocrine Disruptors; Female; Gossypol; Hippocampus; Mice; Neurogenesis; Neuroinflammatory Diseases; Pregnancy; Prenatal Exposure Delayed Effects | 2021 |
Gossypol Reduces Metastasis and Epithelial-Mesenchymal Transition by Targeting Protease in Human Cervical Cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Movement; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Gossypol; HeLa Cells; Heterografts; Humans; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Peptide Hydrolases; Phytotherapy; Uterine Cervical Neoplasms | 2021 |
Gossypol Promotes Wnt/
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Cell Line; Cell Proliferation; Disease Models, Animal; Extracellular Matrix Proteins; Female; Gossypol; Intercellular Signaling Peptides and Proteins; Mice, Inbred C57BL; Osteoporosis; Ovariectomy; Promoter Regions, Genetic; Up-Regulation; Wnt Signaling Pathway; X-Ray Microtomography | 2019 |
Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo.
Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; bcl-2 Homologous Antagonist-Killer Protein; Beclin-1; Caspase 3; Caspase 8; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Gossypol; Humans; In Situ Nick-End Labeling; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Transmission; Proto-Oncogene Proteins c-bcl-2; Xenograft Model Antitumor Assays | 2014 |
Gossypol has anti-cancer effects by dual-targeting MDM2 and VEGF in human breast cancer.
Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Gossypol; Humans; Mice; Protein Binding; Protein Interaction Domains and Motifs; Proteolysis; Proto-Oncogene Proteins c-mdm2; RNA Stability; Ubiquitination; Vascular Endothelial Growth Factors; Xenograft Model Antitumor Assays | 2017 |
Dietary intake of cottonseed toxins is hypothesized to be a partial cause of Alzheimer's disorder.
Topics: Aged; Alzheimer Disease; Animals; Cell Membrane Permeability; Cholesterol; Cottonseed Oil; Disease Models, Animal; Female; Gossypol; Humans; Microtubules; Neurofibrillary Tangles; Rats; Risk Factors | 2012 |
Suppression of LPS-induced inflammatory responses by gossypol in RAW 264.7 cells and mouse models.
Topics: Animals; Cell Line; Cytokines; Disease Models, Animal; Gossypium; Gossypol; Humans; Inflammation Mediators; Lipopolysaccharides; Lung; Lung Injury; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C | 2013 |
Gossypol activates pancreatic polyamine catabolism in normal rats and induces acute pancreatitis in transgenic rats over-expressing spermidine/spermine N1-acetyltransferase.
Topics: Acetyltransferases; Acute Disease; Animals; Animals, Genetically Modified; Contraceptive Agents, Male; Disease Models, Animal; Gossypol; Pancreas; Pancreatitis; Polyamines; Rats; Rats, Wistar; Reference Values | 2003 |
Cottonseed-oil byproduct as anticancer radiation sensitiser.
Topics: Animals; Combined Modality Therapy; Cottonseed Oil; Disease Models, Animal; Gossypol; Humans; Male; Mice; Prostatic Neoplasms; Radiation-Sensitizing Agents | 2004 |
Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Biomimetics; Blotting, Western; Cell Line, Tumor; Cyclophosphamide; Disease Models, Animal; Flow Cytometry; Gossypol; Humans; In Vitro Techniques; Lymphoma, B-Cell; Membrane Potential, Mitochondrial; Mice; Microscopy, Confocal; Proto-Oncogene Proteins c-bcl-2; Rituximab; Xenograft Model Antitumor Assays | 2008 |
Experimentally-induced prostatic hyperplasia in young beagles: a model to evaluate the chemotherapeutic effects of gossypol.
Topics: 5-alpha Reductase Inhibitors; Acute Disease; Animals; Aromatase Inhibitors; Disease Models, Animal; Dogs; Enzyme Inhibitors; Estradiol; Gossypol; Kidney; Liver; Male; Prostate; Prostatic Hyperplasia; Testis; Testosterone | 1996 |
Altered vascular response to acetylcholine in conditions of endothelial damage in the isolated perfused rat stomach.
Topics: Acetylcholine; Animals; Blood Flow Velocity; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Gastric Mucosa; Gossypol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Rats; Stomach; Stomach Ulcer; Stress, Physiological; Vasodilator Agents | 2000 |
Antiinflammatory effects of various drugs on acetic acid induced colitis in the rat.
Topics: Acetates; Acetic Acid; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Dexamethasone; Disease Models, Animal; Gossypol; Hydrocortisone; Indomethacin; Intestinal Mucosa; Leukocyte Count; Male; Masoprocol; Mesalamine; Neutrophils; Peroxidase; Rats; Rats, Inbred Strains; Sulfasalazine | 1990 |
[Antiviral properties of gossypol in experimental influenza pneumonia].
Topics: Animals; Depression, Chemical; Disease Models, Animal; Gossypol; Mice; Orthomyxoviridae; Pneumonia, Viral; Time Factors | 1970 |