gossypol has been researched along with Diffuse Large B-Cell Lymphoma in 2 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol." | 1.35 | Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo. ( Aboukameel, A; Al-Katib, A; Arnold, AA; Banerjee, S; Chen, J; Lin, Y; Ling, X; Mohammad, RM; Nikolovska-Coleska, Z; Sun, Y; Wang, S; Wu, J; Yang, D, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, Y | 1 |
| Wu, J | 1 |
| Aboukameel, A | 2 |
| Banerjee, S | 1 |
| Arnold, AA | 1 |
| Chen, J | 2 |
| Nikolovska-Coleska, Z | 1 |
| Lin, Y | 1 |
| Ling, X | 1 |
| Yang, D | 1 |
| Wang, S | 2 |
| Al-Katib, A | 2 |
| Mohammad, RM | 2 |
| Chen, B | 1 |
| Wu, X | 1 |
2 other studies available for gossypol and Diffuse Large B-Cell Lymphoma
| Article | Year |
|---|---|
Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo.
Topics: Animals; Apoptosis; bcl-X Protein; Caspase 3; Caspase 9; Cell Death; Cell Line, Tumor; Cell Prolifer | 2008 |
Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(-)-gossypol] against diffuse large cell lymphoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-X Protein; Caspase 3; Caspas | 2005 |