Page last updated: 2024-10-28

gossypol and Di Guglielmo Disease

gossypol has been researched along with Di Guglielmo Disease in 3 studies

Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.

Research Excerpts

ExcerptRelevanceReference
"Gossypol treatments inhibited cell multiplication at 10 and 20 micrograms/ml concentrations and this inhibitory effect increased with elevated dosage and prolonged treatment."1.28Genotoxic effects of gossypol acetic acid on cultured murine erythroleukemia cells. ( Baker, MA; Daehler, CC; Daly, EP; Kleemeyer, KM; Majumdar, SK, 1991)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tuszynski, GP1
Cossu, G1
Haspel, HC1
Ren, YF1
Watanabe, KA1
Sonenberg, M1
Corin, RE1
Majumdar, SK1
Daly, EP1
Kleemeyer, KM1
Daehler, CC1
Baker, MA1

Other Studies

3 other studies available for gossypol and Di Guglielmo Disease

ArticleYear
Differential cytotoxic effect of gossypol on human melanoma, colon carcinoma, and other tissue culture cell lines.
    Cancer research, 1984, Volume: 44, Issue:2

    Topics: Breast Neoplasms; Cell Division; Cell Line; Colonic Neoplasms; Fibroblasts; Gossypol; Humans; Leukem

1984
Cytocidal effect of gossypol on cultured murine erythroleukemia cells is prevented by serum protein.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:1

    Topics: Animals; Blood Proteins; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Gossypol; L

1984
Genotoxic effects of gossypol acetic acid on cultured murine erythroleukemia cells.
    Environmental and molecular mutagenesis, 1991, Volume: 18, Issue:3

    Topics: Animals; Cell Division; Cell Membrane; Chromosome Aberrations; DNA Damage; DNA Replication; Gossypol

1991