gossypol has been researched along with Congenital Zika Syndrome in 3 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We previously identified gossypol as an effective inhibitor against ZIKV and DENV infections, but this compound is toxic and not suitable for in vivo treatment." | 5.72 | A gossypol derivative effectively protects against Zika and dengue virus infection without toxicity. ( Chen, S; Debnath, AK; Du, L; Gao, Y; Jiang, S; Tai, W; Wang, X, 2022) |
| " We previously identified gossypol as an effective inhibitor against ZIKV and DENV infections, but this compound is toxic and not suitable for in vivo treatment." | 1.72 | A gossypol derivative effectively protects against Zika and dengue virus infection without toxicity. ( Chen, S; Debnath, AK; Du, L; Gao, Y; Jiang, S; Tai, W; Wang, X, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Gao, Y | 2 |
| Tai, W | 2 |
| Wang, X | 1 |
| Jiang, S | 2 |
| Debnath, AK | 2 |
| Du, L | 2 |
| Chen, S | 2 |
| Wang, N | 1 |
| Li, X | 1 |
3 other studies available for gossypol and Congenital Zika Syndrome
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
A gossypol derivative effectively protects against Zika and dengue virus infection without toxicity.
Topics: Animals; Cross Reactions; Dengue; Dengue Virus; Female; Gossypol; Male; Mice; Pregnancy; Zika Virus; | 2022 |
Identification of Novel Natural Products as Effective and Broad-Spectrum Anti-Zika Virus Inhibitors.
Topics: Alkaloids; Animals; Antiviral Agents; Biological Products; Cell Survival; Chlorocebus aethiops; Curc | 2019 |