gossypol has been researched along with Colorectal Cancer in 5 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5/3-mda-7 alone or in combination with BI-97C1 would be predicted to exert significantly improved therapeutic efficacy in colorectal cancer patients." | 5.38 | Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells. ( Azab, B; Bhutia, SK; Curiel, DT; Das, SK; Dash, R; Dent, P; Dmitriev, IP; Fisher, PB; Grant, S; Hedvat, M; Pellecchia, M; Quinn, BA; Reed, JC; Sarkar, D; Sarkar, S; Shen, XN; Wang, XY, 2012) |
| " The method was implemented with anticancer activity of Gossypol acetic acid against BCL2 target for colorectal cancer." | 3.79 | Development of method for three-point data estimation and SVR-QSAR model to screen anti cancer leads. ( Khan, F; Prakash, O, 2013) |
| "5/3-mda-7 alone or in combination with BI-97C1 would be predicted to exert significantly improved therapeutic efficacy in colorectal cancer patients." | 1.38 | Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells. ( Azab, B; Bhutia, SK; Curiel, DT; Das, SK; Dash, R; Dent, P; Dmitriev, IP; Fisher, PB; Grant, S; Hedvat, M; Pellecchia, M; Quinn, BA; Reed, JC; Sarkar, D; Sarkar, S; Shen, XN; Wang, XY, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prakash, O | 1 |
| Khan, F | 1 |
| Li, T | 1 |
| Yuan, G | 1 |
| Zhang, L | 1 |
| Ye, L | 1 |
| Li, S | 1 |
| Fan, Y | 1 |
| Sun, J | 1 |
| Azab, B | 1 |
| Dash, R | 1 |
| Das, SK | 1 |
| Bhutia, SK | 1 |
| Shen, XN | 1 |
| Quinn, BA | 1 |
| Sarkar, S | 1 |
| Wang, XY | 1 |
| Hedvat, M | 1 |
| Dmitriev, IP | 1 |
| Curiel, DT | 1 |
| Grant, S | 1 |
| Dent, P | 1 |
| Reed, JC | 1 |
| Pellecchia, M | 1 |
| Sarkar, D | 1 |
| Fisher, PB | 1 |
| Chien, CC | 1 |
| Ko, CH | 2 |
| Shen, SC | 2 |
| Yang, LY | 2 |
| Chen, YC | 2 |
| Lin, CW | 1 |
5 other studies available for gossypol and Colorectal Cancer
| Article | Year |
|---|---|
Development of method for three-point data estimation and SVR-QSAR model to screen anti cancer leads.
Topics: Antineoplastic Agents; Colorectal Neoplasms; Gossypol; High-Throughput Screening Assays; Humans; Mod | 2013 |
ApoG2 inhibits the antiapoptotic protein, Mcl‑1, and induces mitochondria‑dependent apoptosis in human colorectal cancer cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Cel | 2015 |
Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells.
Topics: Adenoviridae; Animals; Cell Line, Tumor; Colorectal Neoplasms; Coxsackie and Adenovirus Receptor-Lik | 2012 |
The role of COX-2/PGE2 in gossypol-induced apoptosis of colorectal carcinoma cells.
Topics: Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Ge | 2012 |
Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; bcl-Associated Death Protein; | 2007 |