gossypol has been researched along with Burkitt Lymphoma in 3 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Burkitt Lymphoma: A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Burkitt lymphoma is a highly aggressive B-cell neoplasm." | 5.42 | Valproic Acid Enhances the Anti-tumor Effect of (-)-gossypol to Burkitt Lymphoma Namalwa Cells. ( Chen, XH; Gong, Y; Ni, ZH; Zhang, X; Zou, ZM, 2015) |
| "Burkitt lymphoma is a highly aggressive B-cell neoplasm." | 1.42 | Valproic Acid Enhances the Anti-tumor Effect of (-)-gossypol to Burkitt Lymphoma Namalwa Cells. ( Chen, XH; Gong, Y; Ni, ZH; Zhang, X; Zou, ZM, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, ZY | 1 |
| Xu, F | 1 |
| Sun, R | 1 |
| Chen, YF | 1 |
| Zhang, DS | 1 |
| Fan, YH | 1 |
| Sun, J | 1 |
| Gong, Y | 1 |
| Ni, ZH | 1 |
| Zhang, X | 1 |
| Chen, XH | 1 |
| Zou, ZM | 1 |
| Ni, Z | 1 |
| Dai, X | 1 |
| Wang, B | 1 |
| Ding, W | 1 |
| Cheng, P | 1 |
| Xu, L | 1 |
| Lian, J | 1 |
| He, F | 1 |
3 other studies available for gossypol and Burkitt Lymphoma
| Article | Year |
|---|---|
Apogossypolone induces reactive oxygen species accumulation and controls cell cycle progression in Raji Burkkit's lymphoma cells.
Topics: Antineoplastic Agents; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Checkpoint | 2015 |
Valproic Acid Enhances the Anti-tumor Effect of (-)-gossypol to Burkitt Lymphoma Namalwa Cells.
Topics: Antineoplastic Agents; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Contraceptive Agents, Male; Dr | 2015 |
Natural Bcl-2 inhibitor (-)- gossypol induces protective autophagy via reactive oxygen species-high mobility group box 1 pathway in Burkitt lymphoma.
Topics: Antioxidants; Apoptosis; Autophagy; Burkitt Lymphoma; Cell Line, Tumor; Cytosol; Gossypol; HMGB1 Pro | 2013 |