gossypol has been researched along with African Sleeping Sickness in 3 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gossypol treatment and trypanosomal infection, either alone or in concert, caused an anaemia that was both macrocytic and hypochromic." | 1.29 | The effects of protein malnutrition and experimental infection with Trypanosoma brucei on gossypol treatment in the rat: haematological and serum biochemical changes. ( Aire, TA; Akingbemi, BT; Ogwuegbu, SO; Oke, BO; Onwuka, SK, 1995) |
| "Gossypol treatment or trypanosome infection, either alone or together, invariably caused significant reductions in the serum activity of creatine phosphokinase and amylase and in the serum concentration of cortisol." | 1.29 | Gossypol toxicosis in the rat associated with protein malnutrition and experimental infection with Trypanosoma brucei. ( Aire, TA; Akingbemi, BT; Ogwuegbu, SO; Oke, BO; Onwuka, SK, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akingbemi, BT | 3 |
| Ogwuegbu, SO | 2 |
| Onwuka, SK | 2 |
| Oke, BO | 3 |
| Aire, TA | 3 |
3 other studies available for gossypol and African Sleeping Sickness
| Article | Year |
|---|---|
The effects of protein malnutrition and experimental infection with Trypanosoma brucei on gossypol treatment in the rat: haematological and serum biochemical changes.
Topics: Animals; Blood Cell Count; Blood Chemical Analysis; Gossypol; Male; Nutritional Status; Protein Defi | 1995 |
Infection with Trypanosoma brucei potentiates the antifertility effect of gossypol, especially in the protein-malnourished male rat.
Topics: Animals; Body Weight; Genitalia, Male; Gossypol; Infertility, Male; Male; Microscopy, Electron; Orga | 1996 |
Gossypol toxicosis in the rat associated with protein malnutrition and experimental infection with Trypanosoma brucei.
Topics: Adrenal Glands; Amylases; Animals; Contraindications; Creatine Kinase; Gossypol; Heart; Hydrocortiso | 1996 |