gossypol has been researched along with Acute Lymphoid Leukemia in 2 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Co-treatment with gossypol acetate and dexamethasone notably amplified the pro-apoptosis activity of the latter in Raji cells." | 1.38 | [Effects of gossypol acetate on apoptosis in primary cultured cells from patients with lymphoid leukemia and its synergy with dexamethasone]. ( Cheng, W; Li, YM; Yang, DJ; Zhao, YQ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spijkers-Hagelstein, JA | 1 |
| Schneider, P | 1 |
| Pinhanços, SM | 1 |
| Garrido Castro, P | 1 |
| Pieters, R | 1 |
| Stam, RW | 1 |
| Cheng, W | 1 |
| Zhao, YQ | 1 |
| Li, YM | 1 |
| Yang, DJ | 1 |
2 other studies available for gossypol and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Glucocorticoid sensitisation in Mixed Lineage Leukaemia-rearranged acute lymphoblastic leukaemia by the pan-BCL-2 family inhibitors gossypol and AT-101.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Dose-Response Relationshi | 2014 |
[Effects of gossypol acetate on apoptosis in primary cultured cells from patients with lymphoid leukemia and its synergy with dexamethasone].
Topics: Apoptosis; Cell Line; Dexamethasone; Gossypol; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Precu | 2012 |