gossypol has been researched along with Acute Disease in 3 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results indicate that gossypol induces pancreatitis through an activation of polyamine catabolism." | 7.72 | Gossypol activates pancreatic polyamine catabolism in normal rats and induces acute pancreatitis in transgenic rats over-expressing spermidine/spermine N1-acetyltransferase. ( Alhonen, L; Herzig, KH; Jänne, J; Kaasinen, K; Keinänen, T; Räsänen, TL; Sinervirta, R; Uimari, A, 2003) |
| "This study investigated the effect of gossypol on hyperplastic canine prostates induced with long-term administration of androgen and estrogen." | 5.29 | Experimentally-induced prostatic hyperplasia in young beagles: a model to evaluate the chemotherapeutic effects of gossypol. ( Brueggemeier, RW; Canatan, H; Chang, CJ; Chang, WY; Kulp, SK; Lin, YC; Shidaifat, F; Sugimoto, Y, 1996) |
| "The results indicate that gossypol induces pancreatitis through an activation of polyamine catabolism." | 3.72 | Gossypol activates pancreatic polyamine catabolism in normal rats and induces acute pancreatitis in transgenic rats over-expressing spermidine/spermine N1-acetyltransferase. ( Alhonen, L; Herzig, KH; Jänne, J; Kaasinen, K; Keinänen, T; Räsänen, TL; Sinervirta, R; Uimari, A, 2003) |
| "Gossypol is a highly reactive compound present in cotton (Gossypium spp." | 1.39 | Effectiveness of albumin-conjugated gossypol as an immunogen to prevent gossypol-associated acute hepatotoxicity in rats. ( Fonseca, NB; Gadelha, IC; Oloris, SC; Soto-Blanco, B, 2013) |
| "This study investigated the effect of gossypol on hyperplastic canine prostates induced with long-term administration of androgen and estrogen." | 1.29 | Experimentally-induced prostatic hyperplasia in young beagles: a model to evaluate the chemotherapeutic effects of gossypol. ( Brueggemeier, RW; Canatan, H; Chang, CJ; Chang, WY; Kulp, SK; Lin, YC; Shidaifat, F; Sugimoto, Y, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fonseca, NB | 1 |
| Gadelha, IC | 1 |
| Oloris, SC | 1 |
| Soto-Blanco, B | 1 |
| Räsänen, TL | 1 |
| Alhonen, L | 1 |
| Sinervirta, R | 1 |
| Uimari, A | 1 |
| Kaasinen, K | 1 |
| Keinänen, T | 1 |
| Herzig, KH | 1 |
| Jänne, J | 1 |
| Chang, WY | 1 |
| Shidaifat, F | 1 |
| Chang, CJ | 1 |
| Kulp, SK | 1 |
| Sugimoto, Y | 1 |
| Canatan, H | 1 |
| Brueggemeier, RW | 1 |
| Lin, YC | 1 |
3 other studies available for gossypol and Acute Disease
| Article | Year |
|---|---|
Effectiveness of albumin-conjugated gossypol as an immunogen to prevent gossypol-associated acute hepatotoxicity in rats.
Topics: Acute Disease; Animals; Antibodies; Chemical and Drug Induced Liver Injury; Female; Freund's Adjuvan | 2013 |
Gossypol activates pancreatic polyamine catabolism in normal rats and induces acute pancreatitis in transgenic rats over-expressing spermidine/spermine N1-acetyltransferase.
Topics: Acetyltransferases; Acute Disease; Animals; Animals, Genetically Modified; Contraceptive Agents, Mal | 2003 |
Experimentally-induced prostatic hyperplasia in young beagles: a model to evaluate the chemotherapeutic effects of gossypol.
Topics: 5-alpha Reductase Inhibitors; Acute Disease; Animals; Aromatase Inhibitors; Disease Models, Animal; | 1996 |