gossypol has been researched along with Abnormalities, Drug-Induced in 3 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Treatment of mice with gossypol produced significant adverse effects on the dam and offspring including decreased pregnancy weight gain of the dam and growth retardation of the offspring." | 1.28 | Evidence for embryotoxicity of gossypol in mice and chicks with no evidence of mutagenic activity in the Ames test. ( Booth, GM; Li, YF; Seegmiller, RE, 1989) |
| "Gossypol treatment of males had no effect on the outcome of pregnancy." | 1.27 | The embryotoxicity of gossypol. ( Beaudoin, AR, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, YF | 1 |
| Booth, GM | 1 |
| Seegmiller, RE | 1 |
| Beaudoin, AR | 1 |
| Fishbein, L | 1 |
1 review available for gossypol and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Natural non-nutrient substances in the food chain.
Topics: Abnormalities, Drug-Induced; Alkaloids; Animals; Antithyroid Agents; Arsenic Poisoning; Cadmium Pois | 1972 |
2 other studies available for gossypol and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Evidence for embryotoxicity of gossypol in mice and chicks with no evidence of mutagenic activity in the Ames test.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Chick Embryo; Embryo, Mammalian; Female; Fetal Re | 1989 |
The embryotoxicity of gossypol.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Fetal Resorption; Fetus; Gossypol; | 1985 |