gossypol has been researched along with Abnormalities, Autosome in 8 studies
Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gossypol is a yellowish phenolic compound ocurring naturally in certain species of cotton plants of the family Malvaciae, mostly in the seeds and root bark." | 2.37 | Gossypol: a potential antifertility agent for males. ( Qian, SZ; Wang, ZG, 1984) |
| "Gossypol treatments inhibited cell multiplication at 10 and 20 micrograms/ml concentrations and this inhibitory effect increased with elevated dosage and prolonged treatment." | 1.28 | Genotoxic effects of gossypol acetic acid on cultured murine erythroleukemia cells. ( Baker, MA; Daehler, CC; Daly, EP; Kleemeyer, KM; Majumdar, SK, 1991) |
| "The induced chromosomal aberrations of human target cells indiffusion chamber were used as indices of DNA damage." | 1.27 | [Use of technique of culturing cells in diffusion chamber in host-mediate for testing chromosomal effects of gossypol acetate on human lymphocytes]. ( Ding, YN; Zhang, ZS; Zheng, HZ, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhanataev, AK | 1 |
| Borovskaya, TG | 1 |
| Shcherbakova, BS | 1 |
| Rudoi, BA | 1 |
| Vychuzhanina, AV | 1 |
| Grigor'eva, VA | 1 |
| Kamalova, SI | 1 |
| Durnev, AD | 1 |
| Zhang, ZS | 1 |
| Ding, YN | 1 |
| Zheng, HZ | 1 |
| Qian, SZ | 1 |
| Wang, ZG | 1 |
| Tsui, YC | 1 |
| Creasy, MR | 1 |
| Hultén, MA | 1 |
| Majumdar, SK | 1 |
| Daly, EP | 1 |
| Kleemeyer, KM | 1 |
| Daehler, CC | 1 |
| Baker, MA | 1 |
| Ye, WS | 1 |
| Lang, JC | 1 |
| Hsu, TC | 1 |
| Buttar, HS | 1 |
| Nayak, BN | 1 |
| Chen, Y | 1 |
| Sten, M | 1 |
| Nordenskjöld, M | 1 |
| Lambert, B | 1 |
| Matlin, SA | 1 |
| Zhou, RH | 1 |
1 review available for gossypol and Abnormalities, Autosome
| Article | Year |
|---|---|
Gossypol: a potential antifertility agent for males.
Topics: Animals; Chemical Phenomena; Chemistry; Chromosome Aberrations; Contraceptive Agents, Male; Embryo, | 1984 |
7 other studies available for gossypol and Abnormalities, Autosome
| Article | Year |
|---|---|
Evaluation of Kagocel Genotoxicity.
Topics: Animals; Antiviral Agents; Bone Marrow; Chromosome Aberrations; Comet Assay; Crosses, Genetic; DNA F | 2019 |
[Use of technique of culturing cells in diffusion chamber in host-mediate for testing chromosomal effects of gossypol acetate on human lymphocytes].
Topics: Animals, Laboratory; Chromosome Aberrations; Congenital, Hereditary, and Neonatal Diseases and Abnor | 1984 |
The effect of the male contraceptive agent Gossypol on human lymphocytes in vitro: traditional chromosome breakage, micronuclei, sister chromatid exchange, and cell kinetics.
Topics: Adult; Cell Nucleus; Chromosome Aberrations; Chromosomes; Crossing Over, Genetic; Gossypol; Humans; | 1983 |
Genotoxic effects of gossypol acetic acid on cultured murine erythroleukemia cells.
Topics: Animals; Cell Division; Cell Membrane; Chromosome Aberrations; DNA Damage; DNA Replication; Gossypol | 1991 |
[Clastogenicity of a male contraceptive, gossypol, in mammalian cell cultures with and without metabolic activation by S9 mix].
Topics: Adult; Animals; Biotransformation; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; | 1986 |
Cytogenetic effects of vaginally administered gossypol in murine bone marrow cells.
Topics: Administration, Intravaginal; Animals; Bone Marrow; Cell Nucleus; Chromosome Aberrations; DNA Damage | 1987 |
The effect of gossypol on the frequency of DNA-strand breaks in human leukocytes in vitro.
Topics: Cell Cycle; Cell Survival; Cells, Cultured; Chromosome Aberrations; DNA; Gossypol; Humans; Isomerism | 1986 |