goserelin has been researched along with Thyrotoxicosis* in 1 studies
1 other study(ies) available for goserelin and Thyrotoxicosis
Article | Year |
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Goserelin-induced transient thyrotoxicosis in a hypothyroid woman on L-thyroxine replacement.
An increase in free thyroxine (fT4) and a decrease in thyroid-stimulating hormone (TSH) was observed in a hypothyroid woman on levothyroxine treatment after implantation of goserelin, a gonadotropin-releasing hormone (GnRH) analogue. In the literature no data are available that describe a drug interaction between GnRH analogues and thyroid hormone replacement. Our hypothesis to explain this observation is that goserelin decreased serum thyroxine-binding-globulin (TBG), resulting in an increase in fT4 and thereby a decrease in serum TSH. Topics: Adult; Antineoplastic Agents, Hormonal; Drug Implants; Drug Interactions; Female; Goserelin; Humans; Hypothyroidism; Thyrotoxicosis; Thyrotropin; Thyroxine | 2008 |