go 6976 has been researched along with Malignant Melanoma in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gö6976 but not Gö6983 reversed the E- to N-cadherin switch and as a consequence induced intercellular interactions, profound morphological changes from elongated mesenchymal-like to cuboidal epithelial-like shape, β-catenin translocation from the nucleus to the plasma membrane inhibiting its oncogenic function, and reverting the metastatic potential of the aggressive melanoma cells." | 7.85 | Protein kinase C inhibitor Gö6976 but not Gö6983 induces the reversion of E- to N-cadherin switch and metastatic phenotype in melanoma: identification of the role of protein kinase D1. ( Auclair, C; Eymard, M; Hugonin, C; Karam, M; Merzoug-Larabi, M; Spasojevic, C, 2017) |
| "Gö6976 but not Gö6983 reversed the E- to N-cadherin switch and as a consequence induced intercellular interactions, profound morphological changes from elongated mesenchymal-like to cuboidal epithelial-like shape, β-catenin translocation from the nucleus to the plasma membrane inhibiting its oncogenic function, and reverting the metastatic potential of the aggressive melanoma cells." | 3.85 | Protein kinase C inhibitor Gö6976 but not Gö6983 induces the reversion of E- to N-cadherin switch and metastatic phenotype in melanoma: identification of the role of protein kinase D1. ( Auclair, C; Eymard, M; Hugonin, C; Karam, M; Merzoug-Larabi, M; Spasojevic, C, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uhlenbrock, F | 1 |
| Hagemann-Jensen, M | 1 |
| Kehlet, S | 1 |
| Andresen, L | 1 |
| Pastorekova, S | 1 |
| Skov, S | 1 |
| Merzoug-Larabi, M | 1 |
| Spasojevic, C | 1 |
| Eymard, M | 1 |
| Hugonin, C | 1 |
| Auclair, C | 1 |
| Karam, M | 1 |
| Byers, HR | 1 |
| Boissel, SJ | 1 |
| Tu, C | 1 |
| Park, HY | 1 |
| Szekeres, CK | 1 |
| Trikha, M | 1 |
| Honn, KV | 1 |
| Jørgensen, K | 1 |
| Skrede, M | 1 |
| Cruciani, V | 1 |
| Mikalsen, SO | 1 |
| Slipicevic, A | 1 |
| Flørenes, VA | 1 |
5 other studies available for go 6976 and Malignant Melanoma
| Article | Year |
|---|---|
The NKG2D ligand ULBP2 is specifically regulated through an invariant chain-dependent endosomal pathway.
Topics: Antigens, Differentiation, B-Lymphocyte; Antigens, Surface; Biological Transport; Carbazoles; CD4-Po | 2014 |
Protein kinase C inhibitor Gö6976 but not Gö6983 induces the reversion of E- to N-cadherin switch and metastatic phenotype in melanoma: identification of the role of protein kinase D1.
Topics: Aged; Antigens, CD; Blotting, Western; Cadherins; Carbazoles; Cell Line, Tumor; Enzyme-Linked Immuno | 2017 |
RNAi-mediated knockdown of protein kinase C-alpha inhibits cell migration in MM-RU human metastatic melanoma cell line.
Topics: Apoptosis; Carbazoles; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Movement; Extracellular Mat | 2010 |
12(S)-HETE, pleiotropic functions, multiple signaling pathways.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Carbazoles; Enzyme Inhibitors; Humans; Indoles; Melanoma | 2002 |
Phorbol ester phorbol-12-myristate-13-acetate promotes anchorage-independent growth and survival of melanomas through MEK-independent activation of ERK1/2.
Topics: Anoikis; Apoptosis; Butadienes; Carbazoles; Cell Adhesion; Cell Culture Techniques; Cell Cycle; Cell | 2005 |