go 6976 has been researched along with Cancer of Skin in 3 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gö6976 but not Gö6983 reversed the E- to N-cadherin switch and as a consequence induced intercellular interactions, profound morphological changes from elongated mesenchymal-like to cuboidal epithelial-like shape, β-catenin translocation from the nucleus to the plasma membrane inhibiting its oncogenic function, and reverting the metastatic potential of the aggressive melanoma cells." | 7.85 | Protein kinase C inhibitor Gö6976 but not Gö6983 induces the reversion of E- to N-cadherin switch and metastatic phenotype in melanoma: identification of the role of protein kinase D1. ( Auclair, C; Eymard, M; Hugonin, C; Karam, M; Merzoug-Larabi, M; Spasojevic, C, 2017) |
| "Gö6976 but not Gö6983 reversed the E- to N-cadherin switch and as a consequence induced intercellular interactions, profound morphological changes from elongated mesenchymal-like to cuboidal epithelial-like shape, β-catenin translocation from the nucleus to the plasma membrane inhibiting its oncogenic function, and reverting the metastatic potential of the aggressive melanoma cells." | 3.85 | Protein kinase C inhibitor Gö6976 but not Gö6983 induces the reversion of E- to N-cadherin switch and metastatic phenotype in melanoma: identification of the role of protein kinase D1. ( Auclair, C; Eymard, M; Hugonin, C; Karam, M; Merzoug-Larabi, M; Spasojevic, C, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Merzoug-Larabi, M | 1 |
| Spasojevic, C | 1 |
| Eymard, M | 1 |
| Hugonin, C | 1 |
| Auclair, C | 1 |
| Karam, M | 1 |
| Arun, SN | 1 |
| Xie, D | 1 |
| Dodd, ME | 1 |
| Zhong, X | 1 |
| Bollag, WB | 1 |
| He, YY | 1 |
| Huang, JL | 1 |
| Chignell, CF | 1 |
3 other studies available for go 6976 and Cancer of Skin
| Article | Year |
|---|---|
Protein kinase C inhibitor Gö6976 but not Gö6983 induces the reversion of E- to N-cadherin switch and metastatic phenotype in melanoma: identification of the role of protein kinase D1.
Topics: Aged; Antigens, CD; Blotting, Western; Cadherins; Carbazoles; Cell Line, Tumor; Enzyme-Linked Immuno | 2017 |
The potential use of protein kinase D inhibitors for prevention/treatment of epidermal tumors.
Topics: Animals; Anticarcinogenic Agents; Carbazoles; Cell Differentiation; Cell Proliferation; Cells, Cultu | 2010 |
Delayed and sustained activation of extracellular signal-regulated kinase in human keratinocytes by UVA: implications in carcinogenesis.
Topics: Animals; Apoptosis; Blotting, Western; Calcium; Carbazoles; Caspase 3; Caspases; Cell Line; Cell Lin | 2004 |