go 6976 has been researched along with Cancer of Lung in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, these inhibitors have yet to prove clinically efficacious, and their toxicity in skin, reflecting activity against wild-type EGFR, may limit dosing required to effectively suppress EGFR T790M in vivo." | 1.39 | Noncovalent wild-type-sparing inhibitors of EGFR T790M. ( Chan, E; Heffron, TP; La, H; Lee, HJ; Malek, S; Merchant, M; Pirazzoli, V; Politi, K; Schaefer, G; Settleman, J; Shao, L; Sideris, S; Ubhayakar, S; Yauch, RL; Ye, X, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thompson, R | 1 |
| Meuth, M | 1 |
| Woll, P | 1 |
| Zhu, Y | 1 |
| Danson, S | 1 |
| Taube, E | 1 |
| Jokinen, E | 1 |
| Koivunen, P | 1 |
| Koivunen, JP | 1 |
| Lee, HJ | 1 |
| Schaefer, G | 1 |
| Heffron, TP | 1 |
| Shao, L | 1 |
| Ye, X | 1 |
| Sideris, S | 1 |
| Malek, S | 1 |
| Chan, E | 1 |
| Merchant, M | 1 |
| La, H | 1 |
| Ubhayakar, S | 1 |
| Yauch, RL | 1 |
| Pirazzoli, V | 1 |
| Politi, K | 1 |
| Settleman, J | 1 |
| Lang, W | 1 |
| Wang, H | 1 |
| Ding, L | 1 |
| Xiao, L | 1 |
| Felber, M | 1 |
| Sonnemann, J | 1 |
| Beck, JF | 1 |
5 other studies available for go 6976 and Cancer of Lung
| Article | Year |
|---|---|
Treatment with the Chk1 inhibitor Gö6976 enhances cisplatin cytotoxicity in SCLC cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carbazoles; Carcinoma, Small Cell; Cell C | 2012 |
A novel treatment strategy for EGFR mutant NSCLC with T790M-mediated acquired resistance.
Topics: Carbazoles; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Inhi | 2012 |
Noncovalent wild-type-sparing inhibitors of EGFR T790M.
Topics: Acrylamides; Amino Acid Substitution; Animals; Area Under Curve; Base Sequence; Carbazoles; Cell Lin | 2013 |
Cooperation between PKC-alpha and PKC-epsilon in the regulation of JNK activation in human lung cancer cells.
Topics: Animals; Carbazoles; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Membrane; Cytoplasm | 2004 |
Inhibition of novel protein kinase C-epsilon augments TRAIL-induced cell death in A549 lung cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carbazoles; Carcinoma, Non-Small-Cell Lun | 2007 |