go 6976 has been researched along with Breast Neoplasms in 10 studies
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to investigate the role of protein kinase C (PKC) and extracellular signal-regulated kinase 1/2 (ERK1/2) signaling in tamoxifen (TAM)-induced apoptosis and drug resistance in human breast cancer cells." | 7.78 | Role of PKC-ERK signaling in tamoxifen-induced apoptosis and tamoxifen resistance in human breast cancer cells. ( Fang, J; Huang, J; Li, C; Li, Z; Tian, F; Wang, N; Xie, F, 2012) |
| "The epidermal growth factor (EGF) family of receptors (EGFR) is overproduced in estrogen receptor (ER) negative (-) breast cancer cells." | 7.70 | Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells. ( Biswas, DK; Cruz, AP; Gansberger, E; Pardee, AB, 2000) |
| "This study was designed to investigate the role of protein kinase C (PKC) and extracellular signal-regulated kinase 1/2 (ERK1/2) signaling in tamoxifen (TAM)-induced apoptosis and drug resistance in human breast cancer cells." | 3.78 | Role of PKC-ERK signaling in tamoxifen-induced apoptosis and tamoxifen resistance in human breast cancer cells. ( Fang, J; Huang, J; Li, C; Li, Z; Tian, F; Wang, N; Xie, F, 2012) |
| "The epidermal growth factor (EGF) family of receptors (EGFR) is overproduced in estrogen receptor (ER) negative (-) breast cancer cells." | 3.70 | Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells. ( Biswas, DK; Cruz, AP; Gansberger, E; Pardee, AB, 2000) |
| "ErbB2 overexpression drives oncogenesis in 20-30% cases of breast cancer." | 1.40 | A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells. ( Ahmad, G; Bailey, TA; Band, H; Band, V; Bielecki, TA; George, M; Kelly, DL; Luan, H; Mohapatra, B; Natarajan, A; Raja, SM; Tom, E, 2014) |
| "In some HER2-positive breast tumors, cell surface overexpression of HER2 is not associated with gene amplification but may instead rest in altered gene transcription, half-life, or recycling of the oncoprotein." | 1.34 | Protein kinase Calpha determines HER2 fate in breast carcinoma cells with HER2 protein overexpression without gene amplification. ( Albano, L; Campaner, S; Campiglio, M; Magnifico, A; Ménard, S; Pilotti, S; Tagliabue, E, 2007) |
| "Although ErbB2 is known to enhance breast cancer metastasis, the signaling events responsible for this remain elusive." | 1.33 | Upregulation and activation of PKC alpha by ErbB2 through Src promotes breast cancer cell invasion that can be blocked by combined treatment with PKC alpha and Src inhibitors. ( Li, P; Sun, M; Tan, M; Yin, G; Yu, D, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (80.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bailey, TA | 1 |
| Luan, H | 1 |
| Tom, E | 1 |
| Bielecki, TA | 1 |
| Mohapatra, B | 1 |
| Ahmad, G | 1 |
| George, M | 1 |
| Kelly, DL | 1 |
| Natarajan, A | 1 |
| Raja, SM | 1 |
| Band, V | 1 |
| Band, H | 1 |
| Li, Z | 1 |
| Wang, N | 1 |
| Fang, J | 1 |
| Huang, J | 1 |
| Tian, F | 1 |
| Li, C | 1 |
| Xie, F | 1 |
| Kohn, EA | 1 |
| Yoo, CJ | 1 |
| Eastman, A | 1 |
| Fujii, T | 1 |
| Nakamura, AM | 1 |
| Yokoyama, G | 1 |
| Yamaguchi, M | 1 |
| Tayama, K | 1 |
| Miwa, K | 1 |
| Toh, U | 1 |
| Kawamura, D | 1 |
| Shirouzu, K | 1 |
| Yamana, H | 1 |
| Kuwano, M | 1 |
| Tsuda, H | 1 |
| Wang, HJ | 1 |
| Wu, ZY | 1 |
| Fan, P | 1 |
| Bian, JM | 1 |
| Tan, M | 1 |
| Li, P | 1 |
| Sun, M | 1 |
| Yin, G | 1 |
| Yu, D | 1 |
| Magnifico, A | 1 |
| Albano, L | 1 |
| Campaner, S | 1 |
| Campiglio, M | 1 |
| Pilotti, S | 1 |
| Ménard, S | 1 |
| Tagliabue, E | 1 |
| Lee, HJ | 1 |
| Ji, Y | 1 |
| Paul, S | 1 |
| Maehr, H | 1 |
| Uskokovic, M | 1 |
| Suh, N | 1 |
| Biswas, DK | 2 |
| Cruz, AP | 1 |
| Gansberger, E | 1 |
| Pardee, AB | 2 |
| Dai, SC | 1 |
| Cruz, A | 1 |
| Weiser, B | 1 |
| Graner, E | 1 |
10 other studies available for go 6976 and Breast Neoplasms
| Article | Year |
|---|---|
A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.
Topics: Antineoplastic Agents; Benzoquinones; Breast Neoplasms; Carbazoles; Carcinogenesis; Cell Line, Tumor | 2014 |
Role of PKC-ERK signaling in tamoxifen-induced apoptosis and tamoxifen resistance in human breast cancer cells.
Topics: Acetophenones; Antineoplastic Agents, Hormonal; Apoptosis; Benzopyrans; Breast Neoplasms; Carbazoles | 2012 |
The protein kinase C inhibitor Gö6976 is a potent inhibitor of DNA damage-induced S and G2 cell cycle checkpoints.
Topics: Breast Neoplasms; Carbazoles; Cell Cycle; Cell Survival; DNA Damage; Enzyme Inhibitors; Female; G2 P | 2003 |
Antineoplaston induces G(1) arrest by PKCalpha and MAPK pathway in SKBR-3 breast cancer cells.
Topics: Benzeneacetamides; Blotting, Western; Breast Neoplasms; Carbazoles; Cell Cycle Proteins; Cell Line, | 2005 |
[The nuclear factor kappa B activation: the key step of cell proliferation in estrogen receptor-negative breast cancer cells].
Topics: Breast Neoplasms; Carbazoles; Cell Proliferation; Cyclin D1; Epidermal Growth Factor; Estradiol; Fem | 2005 |
Upregulation and activation of PKC alpha by ErbB2 through Src promotes breast cancer cell invasion that can be blocked by combined treatment with PKC alpha and Src inhibitors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carbazoles; Cell Line, Tumor; Enzy | 2006 |
Protein kinase Calpha determines HER2 fate in breast carcinoma cells with HER2 protein overexpression without gene amplification.
Topics: Breast Neoplasms; Carbazoles; Cell Line, Tumor; Enzyme Inhibitors; Epidermal Growth Factor; Gene Amp | 2007 |
Activation of bone morphogenetic protein signaling by a Gemini vitamin D3 analogue is mediated by Ras/protein kinase C alpha.
Topics: Bone Morphogenetic Proteins; Breast; Breast Neoplasms; Calcitriol; Carbazoles; Cell Line; Cell Line, | 2007 |
Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells.
Topics: Breast Neoplasms; Carbazoles; Cell Cycle; Cyclin D1; Epidermal Growth Factor; ErbB Receptors; Female | 2000 |
The nuclear factor kappa B (NF-kappa B): a potential therapeutic target for estrogen receptor negative breast cancers.
Topics: Animals; Base Sequence; Breast Neoplasms; Carbazoles; Cell Division; Cyclin D1; DNA Primers; Enzyme | 2001 |