Page last updated: 2024-10-28

go 6976 and Bladder Cancer

go 6976 has been researched along with Bladder Cancer in 5 studies

Research Excerpts

ExcerptRelevanceReference
"Treatment of bladder cancer cell lines (T24, 5637) with the PKC-α or Dicer knockdown and the PKC inhibitors (Calphostin C and Gö 6976) can promote the apoptosis."1.42Reduction of protein kinase C α (PKC-α) promote apoptosis via down-regulation of Dicer in bladder cancer. ( Chen, X; Jiang, Z; Kong, C; Zhang, Y; Zhang, Z; Zhu, Y, 2015)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jiang, Z1
Kong, C1
Zhang, Z1
Zhu, Y1
Zhang, Y1
Chen, X1
Aaltonen, V4
Peltonen, J4
Koivunen, J2
Koskela, S2
Lehenkari, P2
Laato, M2
Leinonen, P1
Korkiamäki, T1

Other Studies

5 other studies available for go 6976 and Bladder Cancer

ArticleYear
Reduction of protein kinase C α (PKC-α) promote apoptosis via down-regulation of Dicer in bladder cancer.
    Journal of cellular and molecular medicine, 2015, Volume: 19, Issue:5

    Topics: Apoptosis; Blotting, Western; Carbazoles; Caspase 3; Cell Line, Tumor; Down-Regulation; Enzyme Inhib

2015
PKCalpha/beta I inhibitor Go6976 induces dephosphorylation of constitutively hyperphosphorylated Rb and G1 arrest in T24 cells.
    Anticancer research, 2010, Volume: 30, Issue:10

    Topics: Carbazoles; Carcinoma, Transitional Cell; Cell Line, Tumor; Flow Cytometry; G1 Phase; Genes, p53; Hu

2010
Protein kinase C alpha/beta inhibitor Go6976 promotes formation of cell junctions and inhibits invasion of urinary bladder carcinoma cells.
    Cancer research, 2004, Aug-15, Volume: 64, Issue:16

    Topics: Actins; Adherens Junctions; Carbazoles; Carcinoma, Transitional Cell; Cell Movement; Cytoskeleton; D

2004
PKC inhibitor Go6976 induces mitosis and enhances doxorubicin-paclitaxel cytotoxicity in urinary bladder carcinoma cells.
    Cancer letters, 2007, Aug-08, Volume: 253, Issue:1

    Topics: Carbazoles; Cell Death; DNA Damage; Doxorubicin; Enzyme Inhibitors; G2 Phase; Humans; Indoles; Mitos

2007
Impaired gap junction formation and intercellular calcium signaling in urinary bladder cancer cells can be improved by Gö6976.
    Cell communication & adhesion, 2007, Volume: 14, Issue:4

    Topics: Blotting, Western; Calcium Signaling; Carbazoles; Carcinoma, Transitional Cell; Cell Communication;

2007