glyoxylic acid has been researched along with Nephrolithiasis in 8 studies
glyoxylic acid: RN given refers to parent cpd
glyoxylic acid : A 2-oxo monocarboxylic acid that is acetic acid bearing an oxo group at the alpha carbon atom.
Nephrolithiasis: Formation of stones in the KIDNEY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Results confirm that hyperoxaluria induction alone is not sufficient to create calcium oxalate nephrolithiasis in mice." | 7.76 | Experimental induction of calcium oxalate nephrolithiasis in mice. ( Glenton, PA; Khan, SR, 2010) |
| "Mouse models of nephrolithiasis were established via intraperitoneal injection of glyoxylate, and cell models of tubular epithelial cells and macrophages were established using calcium oxalate monohydrate (COM)." | 4.02 | Vitexin exerts protective effects against calcium oxalate crystal-induced kidney pyroptosis in vivo and in vitro. ( Ding, J; Ding, T; Guo, Z; Ji, B; Li, Y; Liu, Z; Wang, Y; Zhao, T, 2021) |
| " We develop and utilize a glyoxylate induced mouse model of kidney calcium oxalate crystal deposition for studying the pharmacological effects of fasudil, a Rho associated protein kinase (ROCK) specific inhibitor, on the kidney injury and fibrosis caused by calcium oxalate crystallization and deposition." | 3.81 | Fasudil prevents calcium oxalate crystal deposit and renal fibrogenesis in glyoxylate-induced nephrolithic mice. ( Chen, W; Ding, J; Guo, Z; Hu, H; Jia, M; Yin, J, 2015) |
| "Results confirm that hyperoxaluria induction alone is not sufficient to create calcium oxalate nephrolithiasis in mice." | 3.76 | Experimental induction of calcium oxalate nephrolithiasis in mice. ( Glenton, PA; Khan, SR, 2010) |
| "Nephrolithiasis is a systemic metabolic disease with a worldwide incidence that is increasing yearly, as well as a high recurrence rate; however, this disease's pathogenesis has not been thoroughly elucidated to date." | 1.48 | Untargeted lipidomics based on UPLC-QTOF-MS/MS and structural characterization reveals dramatic compositional changes in serum and renal lipids in mice with glyoxylate-induced nephrolithiasis. ( Chao, Y; Dong, X; Gao, S; Li, N; Lou, Z; Wang, X; Wen, X; Zhao, H, 2018) |
| "Hyperoxaluria is a major problem causing nephrolithiasis." | 1.37 | Glyoxylate is a substrate of the sulfate-oxalate exchanger, sat-1, and increases its expression in HepG2 cells. ( Burckhardt, BC; Burckhardt, G; Schnedler, N, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, T | 1 |
| Zhao, T | 1 |
| Li, Y | 1 |
| Liu, Z | 1 |
| Ding, J | 2 |
| Ji, B | 1 |
| Wang, Y | 1 |
| Guo, Z | 3 |
| Chao, Y | 1 |
| Gao, S | 2 |
| Wang, X | 1 |
| Li, N | 1 |
| Zhao, H | 1 |
| Wen, X | 1 |
| Lou, Z | 1 |
| Dong, X | 1 |
| Dindo, M | 1 |
| Conter, C | 1 |
| Oppici, E | 1 |
| Ceccarelli, V | 1 |
| Marinucci, L | 1 |
| Cellini, B | 1 |
| Hu, H | 1 |
| Chen, W | 2 |
| Jia, M | 1 |
| Yin, J | 1 |
| Peng, Z | 1 |
| Wang, L | 1 |
| Ye, Z | 1 |
| Sun, X | 1 |
| Khan, SR | 1 |
| Glenton, PA | 1 |
| Schnedler, N | 1 |
| Burckhardt, G | 1 |
| Burckhardt, BC | 1 |
| Okada, A | 1 |
| Nomura, S | 1 |
| Higashibata, Y | 1 |
| Hirose, M | 1 |
| Gao, B | 1 |
| Yoshimura, M | 1 |
| Itoh, Y | 1 |
| Yasui, T | 1 |
| Tozawa, K | 1 |
| Kohri, K | 1 |
1 review available for glyoxylic acid and Nephrolithiasis
| Article | Year |
|---|---|
Molecular basis of primary hyperoxaluria: clues to innovative treatments.
Topics: Alcohol Oxidoreductases; Calcium Oxalate; Gastrointestinal Microbiome; Genetic Therapy; Glyoxylates; | 2019 |
7 other studies available for glyoxylic acid and Nephrolithiasis
| Article | Year |
|---|---|
Vitexin exerts protective effects against calcium oxalate crystal-induced kidney pyroptosis in vivo and in vitro.
Topics: Animals; Apigenin; Apoptosis; Calcium Oxalate; Cell Line; Disease Models, Animal; Glyoxylates; Human | 2021 |
Untargeted lipidomics based on UPLC-QTOF-MS/MS and structural characterization reveals dramatic compositional changes in serum and renal lipids in mice with glyoxylate-induced nephrolithiasis.
Topics: Animals; Chromatography, High Pressure Liquid; Glyoxylates; Kidney; Lipid Metabolism; Lipids; Male; | 2018 |
Fasudil prevents calcium oxalate crystal deposit and renal fibrogenesis in glyoxylate-induced nephrolithic mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Apoptosis; Cadherins; Calcium Oxalat | 2015 |
Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice.
Topics: Administration, Inhalation; Animals; Apoptosis; Disease Models, Animal; Glyoxylates; Hydrogen; Immun | 2015 |
Experimental induction of calcium oxalate nephrolithiasis in mice.
Topics: Animals; Calcium Oxalate; Disease Models, Animal; Ethylene Glycol; Female; Glyoxylates; Hydroxyproli | 2010 |
Glyoxylate is a substrate of the sulfate-oxalate exchanger, sat-1, and increases its expression in HepG2 cells.
Topics: Animals; Anion Transport Proteins; Base Sequence; DNA Primers; Female; Glycolates; Glyoxylates; Hep | 2011 |
Successful formation of calcium oxalate crystal deposition in mouse kidney by intraabdominal glyoxylate injection.
Topics: Animals; Calcium Oxalate; Crystallization; Ethylene Glycols; Glycolates; Glyoxylates; Immunohistoche | 2007 |