glyoxylic acid has been researched along with Koch's Disease in 6 studies
glyoxylic acid: RN given refers to parent cpd
glyoxylic acid : A 2-oxo monocarboxylic acid that is acetic acid bearing an oxo group at the alpha carbon atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The approval of bedaquiline (BDQ) for the treatment of tuberculosis has generated substantial interest in inhibiting energy metabolism as a therapeutic paradigm." | 7.96 | Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis. ( Adamson, JH; Asmal, R; Beste, DJV; Borah, K; Glasgow, JN; Krieger, I; Lamprecht, DA; Lee, BS; Mackenzie, JS; Pethe, K; Rousseau, S; Sacchettini, JC; Steyn, AJC, 2020) |
| "The approval of bedaquiline (BDQ) for the treatment of tuberculosis has generated substantial interest in inhibiting energy metabolism as a therapeutic paradigm." | 3.96 | Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis. ( Adamson, JH; Asmal, R; Beste, DJV; Borah, K; Glasgow, JN; Krieger, I; Lamprecht, DA; Lee, BS; Mackenzie, JS; Pethe, K; Rousseau, S; Sacchettini, JC; Steyn, AJC, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Mackenzie, JS | 1 |
| Lamprecht, DA | 1 |
| Asmal, R | 1 |
| Adamson, JH | 1 |
| Borah, K | 1 |
| Beste, DJV | 1 |
| Lee, BS | 1 |
| Pethe, K | 1 |
| Rousseau, S | 1 |
| Krieger, I | 1 |
| Sacchettini, JC | 2 |
| Glasgow, JN | 1 |
| Steyn, AJC | 1 |
| Pham, TV | 1 |
| Murkin, AS | 1 |
| Moynihan, MM | 1 |
| Harris, L | 1 |
| Tyler, PC | 1 |
| Shetty, N | 1 |
| Huang, HL | 1 |
| Meek, TD | 1 |
| Serafini, A | 1 |
| Tan, L | 1 |
| Horswell, S | 1 |
| Howell, S | 1 |
| Greenwood, DJ | 1 |
| Hunt, DM | 1 |
| Phan, MD | 1 |
| Schembri, M | 1 |
| Monteleone, M | 1 |
| Montague, CR | 1 |
| Britton, W | 1 |
| Garza-Garcia, A | 1 |
| Snijders, AP | 1 |
| VanderVen, B | 1 |
| Gutierrez, MG | 1 |
| West, NP | 1 |
| de Carvalho, LPS | 1 |
| Lorenz, MC | 1 |
| Fink, GR | 1 |
| Bishai, W | 1 |
| Helmuth, L | 1 |
1 review available for glyoxylic acid and Koch's Disease
| Article | Year |
|---|---|
Life and death in a macrophage: role of the glyoxylate cycle in virulence.
Topics: Candida albicans; Candidiasis; Glyoxylates; Humans; Macrophages; Mycobacterium tuberculosis; Mycoses | 2002 |
5 other studies available for glyoxylic acid and Koch's Disease
| Article | Year |
|---|---|
Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Carbon Cycle; Citric Acid Cycle; D | 2020 |
Mechanism-based inactivator of isocitrate lyases 1 and 2 from
Topics: Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Cysteine; Glyoxylates; Humans; Isocitr | 2017 |
Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism.
Topics: Acyl Coenzyme A; Bacterial Proteins; Citrate (si)-Synthase; Citrates; Fatty Acids; Gene Expression R | 2019 |
Lipid lunch for persistent pathogen.
Topics: Adaptation, Physiological; Animals; Antitubercular Agents; BCG Vaccine; Carbohydrate Metabolism; Gly | 2000 |
Microbiology. A weak link in TB bacterium is found.
Topics: Animals; Antitubercular Agents; Enzyme Inhibitors; Glyoxylates; Isocitrate Lyase; Macrophages; Mice; | 2000 |