Page last updated: 2024-10-18

glyoxylic acid and Kidney Calculi

glyoxylic acid has been researched along with Kidney Calculi in 12 studies

glyoxylic acid: RN given refers to parent cpd
glyoxylic acid : A 2-oxo monocarboxylic acid that is acetic acid bearing an oxo group at the alpha carbon atom.

Kidney Calculi: Stones in the KIDNEY, usually formed in the urine-collecting area of the kidney (KIDNEY PELVIS). Their sizes vary and most contains CALCIUM OXALATE.

Research Excerpts

ExcerptRelevanceReference
"Sirt1 expression in nephrolithiasis patients was downregulated and the level of apoptosis was increased."5.62Sirt1 inhibits kidney stones formation by attenuating calcium oxalate-induced cell injury. ( Ding, DM; Feng, SY; Tian, QX; Wang, DM; Wang, X; Xie, DD; Ye, QL; Yu, DX; Zhang, ZH; Zhang, ZQ, 2021)
"Calcium oxalate (CaOx) stones are the most common type of kidney stones and are associated with high recurrence, short chain fatty acids (SCFAs), and inflammation."4.02Short Chain Fatty Acids Prevent Glyoxylate-Induced Calcium Oxalate Stones by GPR43-Dependent Immunomodulatory Mechanism. ( Chen, X; Gong, L; Jian, Z; Jin, X; Li, H; Liu, Y; Ma, H; Ma, Y; Qi, S; Shu, X; Wang, K; Xiang, L; Zhu, S, 2021)
"In a murine model, the presence of calcium oxalate deposits increases pyelonephritis risk, likely due to preferential aggregation of bacteria on and around calcium oxalate crystals."3.81The Interaction between Enterobacteriaceae and Calcium Oxalate Deposits. ( Barr-Beare, E; Becknell, B; Hains, DS; Hilt, EE; Li, B; Saxena, V; Schober, M; Schwaderer, AL; Thomas-White, K; Wolfe, AJ, 2015)
"Sirt1 expression in nephrolithiasis patients was downregulated and the level of apoptosis was increased."1.62Sirt1 inhibits kidney stones formation by attenuating calcium oxalate-induced cell injury. ( Ding, DM; Feng, SY; Tian, QX; Wang, DM; Wang, X; Xie, DD; Ye, QL; Yu, DX; Zhang, ZH; Zhang, ZQ, 2021)
"Krapp-Hydroxyanthrachinone given orally will, in a dosage of 150-200 mg, inhibit the intra-renal crystallization of calcium oxalate in the rabbit kidney following Glyoxalate intoxication."1.26[Experimental and clinical studies concerning the influence of natural substances on the crystallization of calcium oxalate (author's transl)]. ( Berg, W; Bothor, C; Schneider, HJ, 1982)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's6 (50.00)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Jin, X1
Jian, Z1
Chen, X1
Ma, Y1
Ma, H1
Liu, Y1
Gong, L1
Xiang, L1
Zhu, S1
Shu, X1
Qi, S1
Li, H1
Wang, K1
Wang, B1
Wei, J1
Huangfu, Q1
Gao, F1
Qin, L1
Zhong, J1
Wen, J1
Ye, Z1
Yang, X1
Liu, H1
Ye, QL1
Wang, DM1
Wang, X1
Zhang, ZQ1
Tian, QX1
Feng, SY1
Zhang, ZH1
Yu, DX1
Ding, DM1
Xie, DD1
Usami, M1
Okada, A4
Taguchi, K2
Hamamoto, S4
Kohri, K4
Yasui, T4
Xi, J1
Chen, Y1
Jing, J1
Zhang, Y1
Liang, C1
Hao, Z1
Zhang, L1
Sugino, T1
Unno, R1
Ando, R1
Mogami, T1
Yamashita, H1
Barr-Beare, E1
Saxena, V1
Hilt, EE1
Thomas-White, K1
Schober, M1
Li, B1
Becknell, B1
Hains, DS1
Wolfe, AJ1
Schwaderer, AL1
Fujii, Y1
Niimi, K1
Hirose, M2
Kojima, Y1
Itoh, Y1
Tozawa, K2
Hayashi, Y2
Higashibata, Y1
Gao, B1
Shimizu, H1
Kubota, Y1
Menon, M1
Mahle, CJ1
Berg, W1
Bothor, C1
Schneider, HJ1
García, A1
Muros, M1
Barbas, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Asymptomatic Renal Calculi in Recurrent UTIs: a Prospective Observational Cohort Study[NCT04495699]80 participants (Anticipated)Observational [Patient Registry]2020-09-09Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for glyoxylic acid and Kidney Calculi

ArticleYear
Oxalate metabolism and renal calculi.
    The Journal of urology, 1982, Volume: 127, Issue:1

    Topics: Animals; Biological Transport; Calcium Oxalate; Diet; Gastrointestinal Diseases; Glyoxylates; Humans

1982

Other Studies

11 other studies available for glyoxylic acid and Kidney Calculi

ArticleYear
Short Chain Fatty Acids Prevent Glyoxylate-Induced Calcium Oxalate Stones by GPR43-Dependent Immunomodulatory Mechanism.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Antigens, Ly; Calcium Oxalate; CD24 Antigen; Cell Line; Coculture Techniques; CX3C Chemokin

2021
Identification of Resolvin D1 and Protectin D1 as Potential Therapeutic Agents for Treating Kidney Stones.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Adult; Aged; Animals; Anti-Inflammatory Agents; Antioxidants; Calcium Oxalate; Case-Control Studies;

2022
Sirt1 inhibits kidney stones formation by attenuating calcium oxalate-induced cell injury.
    Chemico-biological interactions, 2021, Sep-25, Volume: 347

    Topics: Aged; Animals; Apoptosis; Calcium Oxalate; Cell Adhesion; Cell Line; Crystallization; Female; Gene S

2021
Genetic differences in C57BL/6 mouse substrains affect kidney crystal deposition.
    Urolithiasis, 2018, Volume: 46, Issue:6

    Topics: Animals; Calcium Oxalate; Disease Models, Animal; Exons; Genetic Variation; Glyoxylates; Kidney; Kid

2018
Sirtuin 3 suppresses the formation of renal calcium oxalate crystals through promoting M2 polarization of macrophages.
    Journal of cellular physiology, 2019, Volume: 234, Issue:7

    Topics: Animals; Calcium Oxalate; Cell Line; Coculture Techniques; Cytokines; Forkhead Box Protein O1; Gene

2019
Brown adipocytes and β
    American journal of physiology. Renal physiology, 2019, 06-01, Volume: 316, Issue:6

    Topics: Adipocytes, Brown; Adipogenesis; Adipose Tissue, Brown; Adrenergic beta-3 Receptor Agonists; Animals

2019
The Interaction between Enterobacteriaceae and Calcium Oxalate Deposits.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Adolescent; Animals; Calcium Oxalate; Child; Disease Models, Animal; DNA, Bacterial; Enterobacteriac

2015
Renal macrophage migration and crystal phagocytosis via inflammatory-related gene expression during kidney stone formation and elimination in mice: Detection by association analysis of stone-related gene expression and microstructural observation.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2010, Volume: 25, Issue:12

    Topics: Animals; Calcium Oxalate; Cell Movement; Gene Expression Regulation; Genetic Association Studies; Gl

2010
Role of osteopontin in early phase of renal crystal formation: immunohistochemical and microstructural comparisons with osteopontin knock-out mice.
    Urological research, 2012, Volume: 40, Issue:2

    Topics: Animals; Calcium Oxalate; Crystallization; Glyoxylates; Kidney; Kidney Calculi; Kidney Tubules, Dist

2012
[Experimental and clinical studies concerning the influence of natural substances on the crystallization of calcium oxalate (author's transl)].
    Der Urologe. Ausg. A, 1982, Volume: 21, Issue:1

    Topics: Animals; Calcium Oxalate; Chlorophyllides; Crystallization; Drug Interactions; Glyoxylates; Humans;

1982
Measurement of nephrolithiasis urinary markers by capillary electrophoresis.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, May-05, Volume: 755, Issue:1-2

    Topics: Biomarkers; Citric Acid; Electrophoresis, Capillary; Glyceric Acids; Glyoxylates; Humans; Kidney Cal

2001